Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRIM40
  • Mouse genes Trim40
  • Rat genes Trim40
  • Zfish genes si:ch211-114c12.5,si:ch211-120g10.1,si:ch73-364h19.2,si:dkey-18p12.4,si:dkey-219e21.2,zgc:194990
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trim40

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TRIM40	IPI	UniProtKB:O14920	Human	PMID:21474709
Molecular Function	GO:0005515	protein binding	TRIM40	IPI	UniProtKB:O15111	Human	PMID:21474709
Molecular Function	GO:0005515	protein binding	TRIM40	IPI	UniProtKB:Q15843	Human	PMID:21474709
Molecular Function	GO:0005515	protein binding	TRIM40	IPI	UniProtKB:Q9Y6K9	Human	PMID:21474709
Cellular Component	GO:0008385	IkappaB kinase complex	TRIM40	IDA		Human	PMID:21474709
Biological Process	GO:0030308	negative regulation of cell growth	Trim40	IMP		Rat	PMID:21474709|RGD:8553878
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	TRIM40	IDA		Human	PMID:21474709
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	Trim40	IMP		Rat	PMID:21474709|RGD:8553878
Biological Process	GO:0042177	negative regulation of protein catabolic process	TRIM40	IDA		Human	PMID:21474709
Biological Process	GO:1900181	negative regulation of protein localization to nucleus	TRIM40	IDA		Human	PMID:21474709
Biological Process	GO:0045116	protein neddylation	TRIM40	IDA		Human	PMID:21474709

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern