Comparative GO Graph (mouse, human)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRIM56
  • Mouse genes Trim56
  • Rat genes
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trim56

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140677	molecular function activator activity	TRIM56	IDA		Human	PMID:29426904
Molecular Function	GO:0005515	protein binding	TRIM56	IPI	UniProtKB:Q8IUC6	Human	PMID:22948160
Molecular Function	GO:0005515	protein binding	Trim56	IPI	UniProtKB:Q3TBT3	Mouse	MGI:MGI:4849871|PMID:21074459
Molecular Function	GO:0003723	RNA binding	TRIM56	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	TRIM56	HDA		Human	PMID:22681889
Molecular Function	GO:0061630	ubiquitin protein ligase activity	TRIM56	IDA		Human	PMID:29426904
Molecular Function	GO:0061630	ubiquitin protein ligase activity	TRIM56	IDA		Human	PMID:35952808
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Trim56	IDA		Mouse	MGI:MGI:6119245|PMID:29426904
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Trim56	IDA		Mouse	PMID:21074459
Cellular Component	GO:0005737	cytoplasm	Trim56	IDA		Mouse	MGI:MGI:4849871|PMID:21074459
Biological Process	GO:0051607	defense response to virus	TRIM56	IDA		Human	PMID:29426904
Biological Process	GO:0051607	defense response to virus	Trim56	IDA		Mouse	MGI:MGI:6119245|PMID:29426904
Biological Process	GO:0051607	defense response to virus	Trim56	IMP		Mouse	MGI:MGI:4849871|PMID:21074459
Biological Process	GO:0045087	innate immune response	Trim56	IDA		Mouse	MGI:MGI:5545996|PMID:18248090
Biological Process	GO:0046597	negative regulation of viral entry into host cell	Trim56	IDA		Mouse	MGI:MGI:5545996|PMID:18248090
Biological Process	GO:0045089	positive regulation of innate immune response	TRIM56	IDA		Human	PMID:29426904
Biological Process	GO:0032728	positive regulation of interferon-beta production	Trim56	IMP		Mouse	MGI:MGI:4849871|PMID:21074459
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	TRIM56	IDA		Human	PMID:35952808
Biological Process	GO:0060340	positive regulation of type I interferon-mediated signaling pathway	TRIM56	IDA		Human	PMID:29426904
Biological Process	GO:0060340	positive regulation of type I interferon-mediated signaling pathway	Trim56	IDA		Mouse	MGI:MGI:6119245|PMID:29426904
Biological Process	GO:0070534	protein K63-linked ubiquitination	Trim56	IDA		Mouse	MGI:MGI:4849871|PMID:21074459
Biological Process	GO:0006513	protein monoubiquitination	TRIM56	IDA		Human	PMID:29426904
Biological Process	GO:0006513	protein monoubiquitination	Trim56	IDA		Mouse	MGI:MGI:6119245|PMID:29426904
Biological Process	GO:0034340	response to type I interferon	Trim56	IDA		Mouse	MGI:MGI:4849871|PMID:21074459
Biological Process	GO:0044790	suppression of viral release by host	Trim56	IDA		Mouse	MGI:MGI:5545996|PMID:18248090

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern