Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRIM58
  • Mouse genes Trim58
  • Rat genes Trim58
  • Zfish genes btr04,btr05,btr06,btr07,btr18,btr20,btr21,btr22,btr23,btr24,btr25,btr26,btr29,btr32,si:ch211-216p19.6,si:dkey-46i9.6,zgc:173581
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trim58

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045504	dynein heavy chain binding	Trim58	IDA		Mouse	MGI:MGI:5908531|PMID:25241935
Molecular Function	GO:0045505	dynein intermediate chain binding	Trim58	IDA		Mouse	MGI:MGI:5908531|PMID:25241935
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Trim58	IDA		Mouse	MGI:MGI:5908531|PMID:25241935
Molecular Function	GO:0061630	ubiquitin protein ligase activity	btr20	IDA		Zfish	PMID:25542153
Cellular Component	GO:0005737	cytoplasm	btr20	IDA		Zfish	PMID:25542153
Biological Process	GO:0061931	positive regulation of erythrocyte enucleation	Trim58	IMP		Mouse	MGI:MGI:5908531|PMID:25241935
Biological Process	GO:0051865	protein autoubiquitination	Trim58	IDA		Mouse	MGI:MGI:5908531|PMID:25241935
Biological Process	GO:0000209	protein polyubiquitination	Trim58	IDA		Mouse	MGI:MGI:5908531|PMID:25241935
Biological Process	GO:1902838	regulation of nuclear migration along microtubule	Trim58	IMP		Mouse	MGI:MGI:5908531|PMID:25241935
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Trim58	IMP		Mouse	MGI:MGI:5908531|PMID:25241935

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern