Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRIM63
  • Mouse genes Trim63
  • Rat genes Trim63
  • Zfish genes trim63a,trim63b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trim63

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TRIM63	IPI	UniProtKB:P26641	Human	PMID:18157088
Molecular Function	GO:0005515	protein binding	TRIM63	IPI	UniProtKB:Q8IX12	Human	PMID:18157088
Molecular Function	GO:0005515	protein binding	TRIM63	IPI	UniProtKB:Q8IXM3	Human	PMID:18157088
Molecular Function	GO:0005515	protein binding	TRIM63	IPI	UniProtKB:Q8WZ42	Human	PMID:18157088
Molecular Function	GO:0005515	protein binding	TRIM63	IPI	UniProtKB:Q96RP9	Human	PMID:18157088
Molecular Function	GO:0005515	protein binding	TRIM63	IPI	UniProtKB:Q9NP98	Human	PMID:18157088
Molecular Function	GO:0005515	protein binding	TRIM63	IPI	UniProtKB:Q8WZ42	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	TRIM63	IPI	UniProtKB:Q5TAQ9	Human	PMID:31391242
Molecular Function	GO:0005515	protein binding	TRIM63	IPI	UniProtKB:Q92995	Human	PMID:31391242
Molecular Function	GO:0005515	protein binding	TRIM63	IPI	UniProtKB:Q08426	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Trim63	IPI	PR:P48787	Mouse	PMID:15601779
Molecular Function	GO:0031432	titin binding	TRIM63	IDA		Human	PMID:11927605
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Trim63	IDA		Mouse	PMID:15601779
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Trim63	IDA		Rat	PMID:11679633|RGD:633893
Cellular Component	GO:0043292	contractile fiber	Trim63	IDA		Rat	PMID:15601779|RGD:8553397
Cellular Component	GO:0005737	cytoplasm	TRIM63	IDA		Human	PMID:11927605
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	Trim63	IDA		Mouse	PMID:23752591
Biological Process	GO:0006936	muscle contraction	Trim63	IDA		Rat	PMID:15601779|RGD:8553397
Biological Process	GO:0010614	negative regulation of cardiac muscle hypertrophy	Trim63	IMP		Rat	PMID:24117217|RGD:11079185
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Trim63	IDA		Mouse	PMID:15601779
Biological Process	GO:0006513	protein monoubiquitination	Trim63	IDA		Mouse	MGI:MGI:6377905|PMID:26862156
Biological Process	GO:0010468	regulation of gene expression	Trim63	IMP		Mouse	PMID:19850579
Biological Process	GO:0014894	response to denervation involved in regulation of muscle adaptation	Trim63	IDA		Mouse	MGI:MGI:5508727|PMID:21465538
Biological Process	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	Trim63	IDA		Rat	PMID:21465538|RGD:8553783
Biological Process	GO:0051384	response to glucocorticoid	Trim63	IEP		Rat	PMID:11679633|RGD:633893
Biological Process	GO:0070555	response to interleukin-1	Trim63	IEP		Rat	PMID:11679633|RGD:633893
Biological Process	GO:0014732	skeletal muscle atrophy	Trim63	IEP		Rat	PMID:11679633|RGD:633893

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern