Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRIM66
  • Mouse genes Trim66
  • Rat genes Trim66
  • Zfish genes trim66
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trim66

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Trim66	IDA		Mouse	PMID:24105743
Molecular Function	GO:0042802	identical protein binding	Trim66	IPI	PR:Q5SEK5	Mouse	PMID:15322135
Molecular Function	GO:0005515	protein binding	Trim66	IPI	PR:P83917	Mouse	PMID:15322135
Molecular Function	GO:0005515	protein binding	Trim66	IPI	PR:Q61686	Mouse	PMID:15322135
Molecular Function	GO:0005515	protein binding	Trim66	IPI	PR:P63058	Mouse	PMID:15322135
Molecular Function	GO:0005515	protein binding	Trim66	IPI	PR:P23198	Mouse	PMID:15322135
Cellular Component	GO:0016235	aggresome	TRIM66	IDA		Human	GO_REF:0000052
Cellular Component	GO:0010369	chromocenter	Trim66	IDA		Mouse	PMID:15322135
Cellular Component	GO:0005654	nucleoplasm	TRIM66	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TRIM66	IDA		Human	PMID:25593309
Cellular Component	GO:0005634	nucleus	Trim66	IDA		Mouse	PMID:15322135
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Trim66	IDA		Mouse	PMID:15322135

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern