Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRIM71
  • Mouse genes Trim71
  • Rat genes Trim71
  • Zfish genes trim71
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trim71

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035198	miRNA binding	TRIM71	IDA		Human	PMID:28431233
Molecular Function	GO:0035198	miRNA binding	Trim71	IDA		Mouse	MGI:MGI:5448492|PMID:22735451
Molecular Function	GO:0005515	protein binding	TRIM71	IPI	UniProtKB:P11940|UniProtKB:Q14671|UniProtKB:Q8IZH2|UniProtKB:Q8TB72|UniProtKB:Q9H0D6|UniProtKB:Q9HCE1|UniProtKB:Q9NUL3|UniProtKB:Q9UKV8	Human	PMID:23125361
Molecular Function	GO:0005515	protein binding	Trim71	IPI	UniProtKB:Q9Z179	Mouse	MGI:MGI:5319563|PMID:22508726
Molecular Function	GO:0005515	protein binding	Trim71	IPI	UniProtKB:Q8CJG0	Mouse	MGI:MGI:5448492|PMID:22735451
Molecular Function	GO:0005515	protein binding	Trim71	IPI	UniProtKB:Q8CJG0	Mouse	MGI:MGI:4438512|PMID:19898466
Molecular Function	GO:0030371	translation repressor activity	TRIM71	IDA		Human	PMID:23125361
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Trim71	IDA		Mouse	PMID:22508726
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Trim71	IDA		Mouse	PMID:19898466
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Trim71	IDA		Mouse	MGI:MGI:5319563|PMID:22508726
Cellular Component	GO:0000932	P-body	TRIM71	IDA		Human	PMID:23125361
Cellular Component	GO:0000932	P-body	Trim71	IDA		Mouse	MGI:MGI:5319563|PMID:22508726
Cellular Component	GO:0000932	P-body	Trim71	IDA		Mouse	MGI:MGI:5448492|PMID:22735451
Cellular Component	GO:0000932	P-body	Trim71	IDA		Mouse	PMID:19898466
Biological Process	GO:0061158	3'-UTR-mediated mRNA destabilization	TRIM71	IDA		Human	PMID:23125361
Biological Process	GO:0071310	cellular response to organic substance	Trim71	IDA		Mouse	PMID:18604195
Biological Process	GO:0010172	embryonic body morphogenesis	trim71	IMP	ZFIN:ZDB-MRPHLNO-080122-1	Zfish	PMID:17890240
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	Trim71	IMP		Mouse	MGI:MGI:5319563|PMID:22508726
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	Trim71	IMP		Mouse	MGI:MGI:5448492|PMID:22735451
Biological Process	GO:0010586	miRNA metabolic process	Trim71	IDA		Mouse	MGI:MGI:5448492|PMID:22735451
Biological Process	GO:0035196	miRNA processing	TRIM71	IMP		Human	PMID:28431233
Biological Process	GO:0035278	miRNA-mediated gene silencing by inhibition of translation	Trim71	IMP		Mouse	MGI:MGI:5448492|PMID:22735451
Biological Process	GO:0017148	negative regulation of translation	TRIM71	IDA		Human	PMID:23125361
Biological Process	GO:0001843	neural tube closure	Trim71	IMP	MGI:MGI:4123844	Mouse	PMID:19098426
Biological Process	GO:0021915	neural tube development	Trim71	IDA		Mouse	MGI:MGI:5319563|PMID:22508726
Biological Process	GO:2000637	positive regulation of miRNA-mediated gene silencing	Trim71	IMP		Mouse	PMID:19898466
Biological Process	GO:2000637	positive regulation of miRNA-mediated gene silencing	Trim71	IDA		Mouse	PMID:19898466
Biological Process	GO:0010608	post-transcriptional regulation of gene expression	TRIM71	IMP		Human	PMID:28431233
Biological Process	GO:0051865	protein autoubiquitination	Trim71	IDA		Mouse	MGI:MGI:5319563|PMID:22508726
Biological Process	GO:0060964	regulation of miRNA-mediated gene silencing	Trim71	IMP		Mouse	MGI:MGI:5448492|PMID:22735451
Biological Process	GO:0060964	regulation of miRNA-mediated gene silencing	Trim71	IGI	MGI:MGI:1890546	Mouse	PMID:19898466
Biological Process	GO:2000177	regulation of neural precursor cell proliferation	Trim71	IMP		Mouse	MGI:MGI:5319563|PMID:22508726
Biological Process	GO:0051246	regulation of protein metabolic process	Trim71	IDA		Mouse	PMID:19898466
Biological Process	GO:0072089	stem cell proliferation	Trim71	IMP		Mouse	MGI:MGI:5448492|PMID:22735451

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern