Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TP53BP2
  • Mouse genes Trp53bp2
  • Rat genes Tp53bp2
  • Zfish genes tp53bp2a,tp53bp2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trp53bp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	TP53BP2	IPI	UniProtKB:Q13625	Human	PMID:18448430
Molecular Function	GO:0051059	NF-kappaB binding	TP53BP2	IPI	UniProtKB:Q04206	Human	PMID:10498867
Molecular Function	GO:0002039	p53 binding	TP53BP2	IPI	UniProtKB:P04637	Human	PMID:14985081
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:O95996	Human	PMID:10646860
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P05067	Human	PMID:11278849
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P04637	Human	PMID:11684014
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:Q13564	Human	PMID:12694406
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:O15350	Human	PMID:14729977
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:Q9H3D4	Human	PMID:14729977
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P04637	Human	PMID:14985081
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P27958:PRO_0000037566	Human	PMID:14985081
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P63104	Human	PMID:15161933
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P62136	Human	PMID:15231748
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:O15350	Human	PMID:18275817
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P04637	Human	PMID:18275817
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:Q9H3D4	Human	PMID:18275817
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P36873	Human	PMID:18448430
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:Q04206	Human	PMID:18448430
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:Q92843	Human	PMID:18448430
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P10415	Human	PMID:18719108
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:Q07817-1	Human	PMID:18719108
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:Q92843	Human	PMID:18719108
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:Q86XP3	Human	PMID:19377511
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P04637	Human	PMID:21513714
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:Q09472	Human	PMID:21513714
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P36873	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P36873	Human	PMID:21998301
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P62136	Human	PMID:21998301
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P62136	Human	PMID:22321011
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P46937	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P36873	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P46937	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P62136	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P62826	Human	PMID:24855949
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P35222	Human	PMID:25344754
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:Q96J02	Human	PMID:25436413
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P04637	Human	PMID:25502805
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P46937	Human	PMID:25751139
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P63104	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P36873	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P62136	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P63104	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P04637	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P46937	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	TP53BP2	IPI	UniProtKB:P04637	Human	PMID:8875926
Cellular Component	GO:0030054	cell junction	TP53BP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	TP53BP2	IDA		Human	PMID:10646860
Cellular Component	GO:0005737	cytoplasm	TP53BP2	IDA		Human	PMID:14985081
Cellular Component	GO:0005737	cytoplasm	TP53BP2	IDA		Human	PMID:19377511
Cellular Component	GO:0005737	cytoplasm	tp53bp2b	IDA		Zfish	PMID:25139857
Cellular Component	GO:0005829	cytosol	TP53BP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TP53BP2	IDA		Human	PMID:19377511
Cellular Component	GO:0005634	nucleus	Tp53bp2	IDA		Rat	PMID:23365256|RGD:8693593
Cellular Component	GO:0048471	perinuclear region of cytoplasm	TP53BP2	IDA		Human	PMID:10646860
Cellular Component	GO:0048471	perinuclear region of cytoplasm	TP53BP2	IDA		Human	PMID:14985081
Biological Process	GO:0007417	central nervous system development	Trp53bp2	IMP	MGI:MGI:3625686	Mouse	PMID:16702401
Biological Process	GO:0043009	chordate embryonic development	tp53bp2a	IMP		Zfish	PMID:24362258
Biological Process	GO:0043009	chordate embryonic development	tp53bp2b	IMP		Zfish	PMID:24362258
Biological Process	GO:0003341	cilium movement	tp53bp2b	IMP	ZFIN:ZDB-MRPHLNO-141110-25	Zfish	PMID:25139857
Biological Process	GO:0009792	embryo development ending in birth or egg hatching	Trp53bp2	IGI	MGI:MGI:98834	Mouse	PMID:16702401
Biological Process	GO:0007507	heart development	Trp53bp2	IMP	MGI:MGI:3625686	Mouse	PMID:16702401
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	TP53BP2	IDA		Human	PMID:11684014
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	tp53bp2a	IMP		Zfish	PMID:24362258
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	tp53bp2b	IMP		Zfish	PMID:24362258
Biological Process	GO:1900119	positive regulation of execution phase of apoptosis	TP53BP2	IMP		Human	PMID:14985081
Biological Process	GO:1901216	positive regulation of neuron death	Tp53bp2	IMP		Rat	PMID:23365256|RGD:8693593
Biological Process	GO:0010212	response to ionizing radiation	Trp53bp2	IMP	MGI:MGI:3625686	Mouse	PMID:16702401

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern