Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Trpm7

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes TRPM7
- Mouse genes Trpm7
- Rat genes Trpm7
- Zfish genes trpm7
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trpm7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Trpm7	IDA		Mouse	PMID:16407977
Molecular Function	GO:0005262	calcium channel activity	Trpm7	IDA		Mouse	PMID:16407977
Molecular Function	GO:0005262	calcium channel activity	Trpm7	IDA		Rat	PMID:12904301\|RGD:1299260
Molecular Function	GO:0016301	kinase activity	Trpm7	IDA		Mouse	PMID:16407977
Molecular Function	GO:0005261	monoatomic cation channel activity	Trpm7	IDA		Rat	PMID:11161216\|RGD:632429
Molecular Function	GO:0017022	myosin binding	Trpm7	IPI	PR:Q8VDD5	Mouse	PMID:16407977
Molecular Function	GO:0005515	protein binding	Trpm7	IPI	UniProtKB:O00571\|UniProtKB:P60710\|UniProtKB:Q3U1J4\|UniProtKB:Q8N488\|UniProtKB:Q8VDD5	Mouse	MGI:MGI:5644004\|PMID:24855944
Molecular Function	GO:0005515	protein binding	Trpm7	IPI	UniProtKB:P60710\|UniProtKB:Q8VDD5	Mouse	MGI:MGI:3613403\|PMID:16407977
Molecular Function	GO:0005515	protein binding	Trpm7	IPI	UniProtKB:P10687	Rat	PMID:11161216\|RGD:632429
Molecular Function	GO:0005515	protein binding	Trpm7	IPI	RGD:1560377	Rat	PMID:17088214\|RGD:5684965
Molecular Function	GO:0005515	protein binding	Trpm7	IPI	RGD:3797	Rat	PMID:17088214\|RGD:5684965
Molecular Function	GO:0005515	protein binding	Trpm7	IPI	RGD:3803	Rat	PMID:17088214\|RGD:5684965
Molecular Function	GO:0004672	protein kinase activity	Trpm7	IDA		Rat	PMID:11161216\|RGD:632429
Cellular Component	GO:0005737	cytoplasm	Trpm7	IDA		Rat	PMID:19322679\|RGD:5684958
Cellular Component	GO:0016020	membrane	Trpm7	IDA		Rat	PMID:12904301\|RGD:1299260
Cellular Component	GO:0043005	neuron projection	Trpm7	IDA		Rat	PMID:17088214\|RGD:5684965
Cellular Component	GO:0043005	neuron projection	Trpm7	IDA		Rat	PMID:18395621\|RGD:5684390
Cellular Component	GO:0043025	neuronal cell body	Trpm7	IDA		Rat	PMID:18395621\|RGD:5684390
Cellular Component	GO:0005886	plasma membrane	Trpm7	IDA		Mouse	PMID:16407977
Cellular Component	GO:0005886	plasma membrane	Trpm7	IDA		Rat	PMID:19322679\|RGD:5684958
Cellular Component	GO:0005886	plasma membrane	trpm7	IDA		Zfish	PMID:27628598
Cellular Component	GO:0001726	ruffle	Trpm7	IDA		Mouse	PMID:16407977
Cellular Component	GO:0030672	synaptic vesicle membrane	Trpm7	IDA		Rat	PMID:17088214\|RGD:5684965
Cellular Component	GO:0043196	varicosity	Trpm7	IDA		Rat	PMID:17088214\|RGD:5684965
Biological Process	GO:0031032	actomyosin structure organization	Trpm7	IDA		Mouse	PMID:16407977
Biological Process	GO:0006816	calcium ion transport	Trpm7	IDA		Mouse	PMID:16407977
Biological Process	GO:0006816	calcium ion transport	Trpm7	IDA		Rat	PMID:12904301\|RGD:1299260
Biological Process	GO:0016340	calcium-dependent cell-matrix adhesion	Trpm7	IDA		Mouse	PMID:16407977
Biological Process	GO:0048066	developmental pigmentation	trpm7	IMP	ZFIN:ZDB-GENO-111011-2	Zfish	PMID:9007256
Biological Process	GO:0031017	exocrine pancreas development	trpm7	IMP	ZFIN:ZDB-GENO-111212-1	Zfish	PMID:21183474
Biological Process	GO:0031017	exocrine pancreas development	trpm7	IMP	ZFIN:ZDB-MRPHLNO-110407-2	Zfish	PMID:21183474
Biological Process	GO:0031017	exocrine pancreas development	trpm7	IMP	ZFIN:ZDB-GENO-111212-2	Zfish	PMID:21183474
Biological Process	GO:0010961	intracellular magnesium ion homeostasis	Trpm7	IMP		Rat	PMID:21487014\|RGD:5684918
Biological Process	GO:0010960	magnesium ion homeostasis	trpm7	IDA		Zfish	PMID:27628598
Biological Process	GO:0006582	melanin metabolic process	trpm7	IMP	ZFIN:ZDB-MRPHLNO-050810-1	Zfish	PMID:17290233
Biological Process	GO:0006582	melanin metabolic process	trpm7	IMP	ZFIN:ZDB-GENO-041111-2	Zfish	PMID:17290233
Biological Process	GO:0006582	melanin metabolic process	trpm7	IMP	ZFIN:ZDB-GENO-070925-1	Zfish	PMID:17290233
Biological Process	GO:0030318	melanocyte differentiation	trpm7	IMP	ZFIN:ZDB-GENO-050810-1	Zfish	PMID:15823540
Biological Process	GO:0030318	melanocyte differentiation	trpm7	IMP	ZFIN:ZDB-GENO-041111-1	Zfish	PMID:15823540
Biological Process	GO:0030318	melanocyte differentiation	trpm7	IMP	ZFIN:ZDB-MRPHLNO-050810-1	Zfish	PMID:15823540
Biological Process	GO:0007613	memory	Trpm7	IMP		Rat	PMID:19734892\|RGD:5684954
Biological Process	GO:0030001	metal ion transport	trpm7	IDA		Zfish	PMID:27628598
Biological Process	GO:0055080	monoatomic cation homeostasis	trpm7	IMP	ZFIN:ZDB-GENO-070925-3	Zfish	PMID:20881241
Biological Process	GO:0070266	necroptotic process	TRPM7	IMP		Human	PMID:24316671
Biological Process	GO:0001503	ossification	trpm7	IMP	ZFIN:ZDB-GENO-050810-1	Zfish	PMID:15823540
Biological Process	GO:0043065	positive regulation of apoptotic process	Trpm7	IMP		Rat	PMID:19734892\|RGD:5684954
Biological Process	GO:0046777	protein autophosphorylation	Trpm7	IDA		Mouse	PMID:16407977
Biological Process	GO:0006468	protein phosphorylation	Trpm7	IDA		Mouse	PMID:16407977
Biological Process	GO:0050678	regulation of epithelial cell proliferation	trpm7	IMP	ZFIN:ZDB-GENO-111212-1	Zfish	PMID:21183474
Biological Process	GO:0050678	regulation of epithelial cell proliferation	trpm7	IMP	ZFIN:ZDB-MRPHLNO-110407-2	Zfish	PMID:21183474
Biological Process	GO:0002027	regulation of heart rate	trpm7	IMP	ZFIN:ZDB-MRPHLNO-130919-1	Zfish	PMID:23878236
Biological Process	GO:0007346	regulation of mitotic cell cycle	trpm7	IMP	ZFIN:ZDB-GENO-111212-1	Zfish	PMID:21183474
Biological Process	GO:0046928	regulation of neurotransmitter secretion	trpm7	IMP	ZFIN:ZDB-GENO-111011-1	Zfish	PMID:21832193
Biological Process	GO:0003014	renal system process	trpm7	IMP	ZFIN:ZDB-GENO-070925-3	Zfish	PMID:20881241
Biological Process	GO:0009314	response to radiation	Trpm7	IEP		Rat	PMID:16201261\|RGD:5685001
Biological Process	GO:0001501	skeletal system development	trpm7	IMP	ZFIN:ZDB-GENO-050810-1	Zfish	PMID:15823540

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/09/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.