Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRPV2
  • Mouse genes Trpv2
  • Rat genes Trpv2
  • Zfish genes trpv1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trpv2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005262	calcium channel activity	Trpv2	IDA		Mouse	PMID:10559903
Molecular Function	GO:0042802	identical protein binding	Trpv2	IPI	UniProtKB:Q9WUD2	Rat	PMID:24373766|RGD:13432316
Molecular Function	GO:0005261	monoatomic cation channel activity	TRPV2	IDA		Human	PMID:10201375
Molecular Function	GO:0005261	monoatomic cation channel activity	Trpv2	IDA		Mouse	PMID:10559903
Molecular Function	GO:0005515	protein binding	TRPV2	IPI	UniProtKB:P0DTC2	Human	PMID:34158856
Molecular Function	GO:0005515	protein binding	Trpv2	IPI	UniProtKB:D3ZH22	Rat	PMID:14991772|RGD:8553756
Cellular Component	GO:0030424	axon	Trpv2	IDA		Mouse	MGI:MGI:4442533|PMID:20357111
Cellular Component	GO:0044295	axonal growth cone	Trpv2	IDA		Mouse	MGI:MGI:4442533|PMID:20357111
Cellular Component	GO:0044297	cell body	Trpv2	IDA		Mouse	MGI:MGI:4442533|PMID:20357111
Cellular Component	GO:0009986	cell surface	Trpv2	IDA		Mouse	MGI:MGI:4442533|PMID:20357111
Cellular Component	GO:0005737	cytoplasm	Trpv2	IDA		Rat	PMID:25869297|RGD:9999444
Cellular Component	GO:0012505	endomembrane system	Trpv2	IDA		Rat	PMID:14991772|RGD:8553756
Cellular Component	GO:0032584	growth cone membrane	Trpv2	IDA		Mouse	MGI:MGI:4442533|PMID:20357111
Cellular Component	GO:0005622	intracellular anatomical structure	Trpv2	IDA		Mouse	PMID:10559903
Cellular Component	GO:0030027	lamellipodium	Trpv2	IDA		Rat	PMID:25869297|RGD:9999444
Cellular Component	GO:0005886	plasma membrane	TRPV2	IDA		Human	PMID:10201375
Cellular Component	GO:0005886	plasma membrane	Trpv2	IDA		Mouse	PMID:10559903
Cellular Component	GO:0005886	plasma membrane	Trpv2	IDA		Rat	PMID:14991772|RGD:8553756
Cellular Component	GO:0005886	plasma membrane	Trpv2	IDA		Rat	PMID:25869297|RGD:9999444
Biological Process	GO:0030317	flagellated sperm motility	trpv1	IMP	ZFIN:ZDB-GENO-210708-22	Zfish	PMID:32251938
Biological Process	GO:0008285	negative regulation of cell population proliferation	Trpv2	IMP		Rat	PMID:25869297|RGD:9999444
Biological Process	GO:0045773	positive regulation of axon extension	Trpv2	IMP		Mouse	MGI:MGI:4442533|PMID:20357111
Biological Process	GO:0090280	positive regulation of calcium ion import	Trpv2	IMP		Mouse	MGI:MGI:4442533|PMID:20357111
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Trpv2	IMP		Mouse	MGI:MGI:5766087|PMID:26882545
Biological Process	GO:0009408	response to heat	Trpv2	IDA		Rat	PMID:10201375|RGD:70055
Biological Process	GO:0009408	response to heat	trpv1	IMP	ZFIN:ZDB-MRPHLNO-130412-4	Zfish	PMID:23516290
Biological Process	GO:0009266	response to temperature stimulus	TRPV2	IDA		Human	PMID:10201375
Biological Process	GO:0040040	thermosensory behavior	trpv1	IMP	ZFIN:ZDB-MRPHLNO-130412-4	Zfish	PMID:23516290

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern