Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TSG101
  • Mouse genes Tsg101
  • Rat genes Tsg101
  • Zfish genes tsg101a,tsg101b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tsg101

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0048306	calcium-dependent protein binding	TSG101	IPI	UniProtKB:Q8WUM4	Human	PMID:19520058
Molecular Function	GO:0030374	nuclear receptor coactivator activity	Tsg101	IDA		Rat	PMID:14761944|RGD:1300501
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:O14964	Human	PMID:12802020
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q99LI8	Human	PMID:12802020
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q99LI8	Human	PMID:12900395
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q86VN1	Human	PMID:14505570
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q8WUM4	Human	PMID:14505570
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q96H20	Human	PMID:14505570
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9UK41	Human	PMID:14505570
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9UK41	Human	PMID:14519844
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9UER7	Human	PMID:15033475
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9NZ52	Human	PMID:15039775
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9H9H4	Human	PMID:15218037
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9UK41	Human	PMID:15218037
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:O75674	Human	PMID:15611048
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q99732	Human	PMID:16118794
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:O14964	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q53EZ4	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q6UWE0	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9UK41	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q86VN1	Human	PMID:16973552
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q96H20	Human	PMID:16973552
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9H3S7	Human	PMID:17174262
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:P46940	Human	PMID:17853893
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q13464	Human	PMID:17853893
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q53EZ4	Human	PMID:17853893
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9Y5K6	Human	PMID:17853893
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q96EY5,UniProtKB:Q9H9H4	Human	PMID:18005716
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q6UWE0	Human	PMID:18077552
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:O75340	Human	PMID:18256029
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q8WUM4	Human	PMID:18641129
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9UK41	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:O60291	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:P05783	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q53EZ4	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q6UWE0	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q53EZ4	Human	PMID:20176808
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q8N5I2	Human	PMID:22315426
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:A1A4E9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:A5D8V6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:O60291	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q15323	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q53EZ4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q6UWE0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q86VP1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q8IZU0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q8N0S2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q8N6Y0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q8NEZ2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q8NEZ2-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q96CS2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9BVG8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9NR12	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9UK41	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9UK41	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q53EZ4	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9NR12	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9UK41	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:O14964	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9UK41-2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:A5D8V6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:A6NC98	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:O76011	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:O95229	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:O95295	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:O95429	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:O95678	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:P05783	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:P08779	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:P80188	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q0VD86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q15025	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q53EZ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q6UWE0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q6ZMJ2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q86T90	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q86VP1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q8N0S2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q8N7C3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q8NBJ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q8NEZ2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q8TC20-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q8TD31-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q8WU39	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q92764	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q96CS2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q96IF1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q96JZ2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q96KN3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q96KQ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q96MT8-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q96PV6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9BQ89	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9BYV2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9H9H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9NR12	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9UBB9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9UK41-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9ULD4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9Y3M2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:O60291	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:P49750	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q14676	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q96IF1	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q96JZ2	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q96KN3	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q96RK0	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	TSG101	IPI	UniProtKB:Q9NZ52	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Tsg101	IPI	UniProtKB:Q9UK41	Mouse	MGI:MGI:5616329|PMID:11134028
Molecular Function	GO:0005515	protein binding	Tsg101	IPI	UniProtKB:Q6UWE0	Mouse	MGI:MGI:3850622|PMID:15256501
Molecular Function	GO:0005515	protein binding	Tsg101	IPI	PR:Q9JI44	Mouse	PMID:10888872
Molecular Function	GO:0005515	protein binding	Tsg101	IPI	PR:Q920G9	Mouse	PMID:12927808
Molecular Function	GO:0042803	protein homodimerization activity	TSG101	IPI	UniProtKB:Q99816	Human	PMID:14519844
Molecular Function	GO:0044877	protein-containing complex binding	TSG101	IDA		Human	PMID:16973552
Molecular Function	GO:0003714	transcription corepressor activity	Tsg101	IDA		Mouse	PMID:10888872
Molecular Function	GO:0043130	ubiquitin binding	TSG101	IDA		Human	PMID:11595185
Molecular Function	GO:0043130	ubiquitin binding	TSG101	IDA		Human	PMID:11916981
Molecular Function	GO:0043130	ubiquitin binding	TSG101	IDA		Human	PMID:20654576
Molecular Function	GO:0031625	ubiquitin protein ligase binding	TSG101	IPI	UniProtKB:O60291	Human	PMID:17229889
Molecular Function	GO:0046790	virion binding	TSG101	IDA		Human	PMID:11595185
Cellular Component	GO:0005737	cytoplasm	TSG101	IDA		Human	PMID:18077552
Cellular Component	GO:0005737	cytoplasm	Tsg101	IDA		Mouse	MGI:MGI:3850622|PMID:15256501
Cellular Component	GO:0005829	cytosol	TSG101	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005769	early endosome	TSG101	IDA		Human	PMID:11916981
Cellular Component	GO:0005769	early endosome	TSG101	IDA		Human	PMID:17229889
Cellular Component	GO:0005768	endosome	TSG101	IDA		Human	PMID:17940959
Cellular Component	GO:0010008	endosome membrane	Tsg101	IDA		Rat	PMID:11134028|RGD:10047383
Cellular Component	GO:0000813	ESCRT I complex	TSG101	IPI		Human	PMID:18005716
Cellular Component	GO:0000813	ESCRT I complex	TSG101	IPI		Human	PMID:21757351
Cellular Component	GO:0000813	ESCRT I complex	TSG101	IPI		Human	PMID:32424346
Cellular Component	GO:0000813	ESCRT I complex	TSG101	IDA		Human	PMID:18005716
Cellular Component	GO:0000813	ESCRT I complex	TSG101	IDA		Human	PMID:20654576
Cellular Component	GO:0000813	ESCRT I complex	TSG101	IDA		Human	PMID:21757351
Cellular Component	GO:0000813	ESCRT I complex	TSG101	IDA		Human	PMID:22232651
Cellular Component	GO:0070062	extracellular exosome	TSG101	IDA		Human	PMID:15326289
Cellular Component	GO:0070062	extracellular exosome	TSG101	IDA		Human	PMID:16501490
Cellular Component	GO:0070062	extracellular exosome	TSG101	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	TSG101	IDA		Human	PMID:23092844
Cellular Component	GO:0070062	extracellular exosome	TSG101	HDA		Human	PMID:23533145
Cellular Component	GO:0070062	extracellular exosome	Tsg101	IDA		Mouse	PMID:24205035
Cellular Component	GO:0005770	late endosome	TSG101	IMP		Human	PMID:15126635
Cellular Component	GO:0005730	nucleolus	TSG101	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Tsg101	IDA		Rat	PMID:14761944|RGD:1300501
Cellular Component	GO:0005886	plasma membrane	TSG101	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	TSG101	IDA		Human	PMID:17940959
Biological Process	GO:0030154	cell differentiation	Tsg101	IDA		Mouse	PMID:11943869
Biological Process	GO:0008333	endosome to lysosome transport	Tsg101	IMP		Rat	PMID:19808888|RGD:4892648
Biological Process	GO:1990182	exosomal secretion	Tsg101	IMP		Mouse	MGI:MGI:5770036|PMID:25392495
Biological Process	GO:0006858	extracellular transport	TSG101	IMP		Human	PMID:22315426
Biological Process	GO:0030216	keratinocyte differentiation	Tsg101	IDA		Mouse	PMID:11943869
Biological Process	GO:0008285	negative regulation of cell population proliferation	Tsg101	IDA		Mouse	PMID:11943869
Biological Process	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	TSG101	IMP		Human	PMID:16554368
Biological Process	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	TSG101	IMP		Human	PMID:16973552
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Tsg101	IDA		Mouse	PMID:10888872
Biological Process	GO:1903543	positive regulation of exosomal secretion	TSG101	IMP		Human	PMID:22660413
Biological Process	GO:1903543	positive regulation of exosomal secretion	TSG101	IMP		Human	PMID:24105262
Biological Process	GO:2000397	positive regulation of ubiquitin-dependent endocytosis	Tsg101	IMP		Mouse	MGI:MGI:5619493|PMID:11916981
Biological Process	GO:1903774	positive regulation of viral budding via host ESCRT complex	TSG101	IMP		Human	PMID:11595185
Biological Process	GO:1903774	positive regulation of viral budding via host ESCRT complex	TSG101	IMP		Human	PMID:15218037
Biological Process	GO:0006513	protein monoubiquitination	Tsg101	IDA		Rat	PMID:14761944|RGD:1300501
Biological Process	GO:0051726	regulation of cell cycle	Tsg101	IDA		Mouse	PMID:11943869
Biological Process	GO:0001558	regulation of cell growth	Tsg101	IDA		Mouse	PMID:11943869
Biological Process	GO:1903551	regulation of extracellular exosome assembly	TSG101	IMP		Human	PMID:24105262
Biological Process	GO:0043405	regulation of MAP kinase activity	TSG101	IMP		Human	PMID:17714434
Biological Process	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	TSG101	IDA		Human	PMID:15611048
Biological Process	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	TSG101	IMP		Human	PMID:21757351
Biological Process	GO:0046755	viral budding	TSG101	IMP		Human	PMID:15126635
Biological Process	GO:0046755	viral budding	TSG101	IMP		Human	PMID:18005716
Biological Process	GO:0046755	viral budding	Tsg101	IMP		Mouse	MGI:MGI:3850622|PMID:15256501
Biological Process	GO:0019076	viral release from host cell	TSG101	IMP		Human	PMID:11595185
Biological Process	GO:0019076	viral release from host cell	TSG101	IMP		Human	PMID:15218037

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern