Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TSLP
  • Mouse genes Tslp
  • Rat genes Tslp
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tslp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005125	cytokine activity	TSLP	IDA		Human	PMID:11418668
Molecular Function	GO:0005125	cytokine activity	TSLP	IMP		Human	PMID:17242164
Molecular Function	GO:0005125	cytokine activity	Tslp	IDA		Mouse	PMID:10974033
Molecular Function	GO:0005139	interleukin-7 receptor binding	TSLP	IMP		Human	PMID:11480573
Molecular Function	GO:0005515	protein binding	Tslp	IPI	UniProtKB:Q8CII9	Mouse	MGI:MGI:5916195|PMID:24632570
Cellular Component	GO:0005576	extracellular region	TSLP	IDA		Human	PMID:11418668
Cellular Component	GO:0005576	extracellular region	TSLP	IMP		Human	PMID:11480573
Cellular Component	GO:0005576	extracellular region	TSLP	IDA		Human	PMID:17242164
Cellular Component	GO:0005615	extracellular space	Tslp	IDA		Mouse	PMID:28811323
Biological Process	GO:0043066	negative regulation of apoptotic process	TSLP	IDA		Human	PMID:11480573
Biological Process	GO:0008284	positive regulation of cell population proliferation	TSLP	IDA		Human	PMID:11418668
Biological Process	GO:0008284	positive regulation of cell population proliferation	TSLP	IMP		Human	PMID:11480573
Biological Process	GO:0071654	positive regulation of chemokine (C-C motif) ligand 1 production	TSLP	IMP		Human	PMID:17242164
Biological Process	GO:0032722	positive regulation of chemokine production	TSLP	IDA		Human	PMID:11418668
Biological Process	GO:0001961	positive regulation of cytokine-mediated signaling pathway	TSLP	IDA		Human	PMID:11418668
Biological Process	GO:0071657	positive regulation of granulocyte colony-stimulating factor production	TSLP	IMP		Human	PMID:17242164
Biological Process	GO:0050729	positive regulation of inflammatory response	TSLP	IMP		Human	PMID:17242164
Biological Process	GO:0032733	positive regulation of interleukin-10 production	TSLP	IMP		Human	PMID:17242164
Biological Process	GO:0032736	positive regulation of interleukin-13 production	TSLP	IMP		Human	PMID:17242164
Biological Process	GO:0032754	positive regulation of interleukin-5 production	TSLP	IMP		Human	PMID:17242164
Biological Process	GO:0032755	positive regulation of interleukin-6 production	TSLP	IMP		Human	PMID:17242164
Biological Process	GO:0033005	positive regulation of mast cell activation	TSLP	IMP		Human	PMID:17242164
Biological Process	GO:1904894	positive regulation of receptor signaling pathway via STAT	TSLP	IDA		Human	PMID:11418668
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	TSLP	IDA		Human	PMID:11480573
Biological Process	GO:0007165	signal transduction	Tslp	IDA		Mouse	MGI:MGI:1889125|PMID:10974033

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern