Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TSPAN4
  • Mouse genes Tspan4
  • Rat genes Tspan4
  • Zfish genes tspan4a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tspan4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003823	antigen binding	TSPAN4	IDA		Human	PMID:9360996
Molecular Function	GO:0005178	integrin binding	TSPAN4	IPI	UniProtKB:P05556	Human	PMID:9360996
Molecular Function	GO:0005178	integrin binding	TSPAN4	IPI	UniProtKB:P23229	Human	PMID:9360996
Molecular Function	GO:0005178	integrin binding	TSPAN4	IPI	UniProtKB:P26006	Human	PMID:9360996
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q7Z3S9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:A0A0C3SFZ9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:A2BDE7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:A8MV65-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:O14633	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:O43559	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:O95470	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:P0DPK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:P28799	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:P32242	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q02930-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q13064	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q3LI66	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q5T5A8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q5T7P2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q5TA76	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q5TA78	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q5TA82	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q8N386	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q8NEC5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q8WW24	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q92570	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q96A25	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q96NT3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q99750	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q9BYE3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q9BYQ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q9BYQ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q9BYQ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q9BYR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q9H2X0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q9H8M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q9NRQ2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q9UHP7-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN4	IPI	UniProtKB:Q9Y223-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Tspan4	IPI	PR:Q60771	Mouse	PMID:11591653
Cellular Component	GO:0005925	focal adhesion	TSPAN4	HDA		Human	PMID:21423176
Cellular Component	GO:0140494	migrasome	Tspan4	IDA		Mouse	PMID:34048705
Cellular Component	GO:0005886	plasma membrane	TSPAN4	IDA		Human	PMID:9360996
Cellular Component	GO:0031982	vesicle	TSPAN4	IDA		Human	PMID:9360996
Biological Process	GO:0160040	mitocytosis	Tspan4	IDA		Mouse	PMID:34048705
Biological Process	GO:0070925	organelle assembly	tspan4a	IMP	ZFIN:ZDB-GENO-200709-5	Zfish	PMID:31371827
Biological Process	GO:0051640	organelle localization	tspan4a	IMP	ZFIN:ZDB-GENO-200709-5	Zfish	PMID:31371827
Biological Process	GO:0065003	protein-containing complex assembly	TSPAN4	IDA		Human	PMID:9360996
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	Tspan4	IDA		Mouse	PMID:34048705

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern