Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Tspo

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes TSPO
- Mouse genes Tspo
- Rat genes Tspo
- Zfish genes tspo
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tspo

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005497	androgen binding	Tspo	IDA		Rat	PMID:8918981\|RGD:2317178
Molecular Function	GO:0008503	benzodiazepine receptor activity	Tspo	IDA		Rat	PMID:2555358\|RGD:634672
Molecular Function	GO:0005515	protein binding	TSPO	IPI	UniProtKB:Q9NRJ1	Human	PMID:17143515
Molecular Function	GO:0005515	protein binding	TSPO	IPI	UniProtKB:Q96BA8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TSPO	IPI	UniProtKB:Q96BA8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TSPO	IPI	UniProtKB:A8MZ59	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPO	IPI	UniProtKB:P15151	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPO	IPI	UniProtKB:P32942	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPO	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPO	IPI	UniProtKB:Q68D85	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPO	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPO	IPI	UniProtKB:Q6UWN5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPO	IPI	UniProtKB:Q86WK6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPO	IPI	UniProtKB:Q8IUN9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPO	IPI	UniProtKB:Q8TAF8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPO	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPO	IPI	UniProtKB:Q9H3M0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPO	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPO	IPI	UniProtKB:Q9P0T7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Tspo	IPI	RGD:620352	Rat	PMID:17174393\|RGD:2317146
Molecular Function	GO:0044325	transmembrane transporter binding	Tspo	IPI	UniProtKB:Q60932	Mouse	MGI:MGI:5689082\|PMID:25470454
Cellular Component	GO:0005829	cytosol	TSPO	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	TSPO	HDA		Human	PMID:19056867
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	TSPO	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005741	mitochondrial outer membrane	Tspo	IDA		Rat	PMID:19863077\|RGD:2317135
Cellular Component	GO:0005739	mitochondrion	TSPO	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Tspo	IDA		Mouse	MGI:MGI:5689082\|PMID:25470454
Cellular Component	GO:0005739	mitochondrion	Tspo	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Tspo	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Tspo	IDA		Rat	PMID:20222126\|RGD:2317129
Biological Process	GO:0030325	adrenal gland development	Tspo	IEP		Rat	PMID:9927316\|RGD:2317174
Biological Process	GO:0007568	aging	Tspo	IEP		Rat	PMID:12002446\|RGD:2317163
Biological Process	GO:0048266	behavioral response to pain	Tspo	IMP		Rat	PMID:19555675\|RGD:2317138
Biological Process	GO:0071476	cellular hypotonic response	Tspo	IEP		Rat	PMID:18709649\|RGD:2317141
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Tspo	IEP		Rat	PMID:14678758\|RGD:2317158
Biological Process	GO:0071294	cellular response to zinc ion	Tspo	IEP		Rat	PMID:18709649\|RGD:2317141
Biological Process	GO:0006821	chloride transport	Tspo	IDA		Rat	PMID:14726306\|RGD:1358441
Biological Process	GO:0042632	cholesterol homeostasis	Tspo	IMP		Rat	PMID:29074640\|RGD:150429771
Biological Process	GO:0060242	contact inhibition	Tspo	IDA		Rat	PMID:18190798\|RGD:2317142
Biological Process	GO:0072655	establishment of protein localization to mitochondrion	Tspo	IMP		Mouse	MGI:MGI:5689082\|PMID:25470454
Biological Process	GO:0008347	glial cell migration	Tspo	IDA		Rat	PMID:18190798\|RGD:2317142
Biological Process	GO:0072656	maintenance of protein location in mitochondrion	Tspo	IMP		Mouse	MGI:MGI:5689082\|PMID:25470454
Biological Process	GO:0006811	monoatomic ion transport	Tspo	IDA		Rat	PMID:14726306\|RGD:1358441
Biological Process	GO:1903579	negative regulation of ATP metabolic process	Tspo	IMP		Mouse	MGI:MGI:5689082\|PMID:25470454
Biological Process	GO:1903147	negative regulation of autophagy of mitochondrion	Tspo	IMP		Mouse	MGI:MGI:5689082\|PMID:25470454
Biological Process	GO:2000853	negative regulation of corticosterone secretion	Tspo	IMP		Rat	PMID:29074640\|RGD:150429771
Biological Process	GO:0060253	negative regulation of glial cell proliferation	Tspo	IDA		Rat	PMID:14678758\|RGD:2317158
Biological Process	GO:0010823	negative regulation of mitochondrion organization	Tspo	IMP		Mouse	MGI:MGI:5689082\|PMID:25470454
Biological Process	GO:0045019	negative regulation of nitric oxide biosynthetic process	Tspo	IDA		Rat	PMID:14678758\|RGD:2317158
Biological Process	GO:0031397	negative regulation of protein ubiquitination	Tspo	IMP		Mouse	MGI:MGI:5689082\|PMID:25470454
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	Tspo	IDA		Rat	PMID:14678758\|RGD:2317158
Biological Process	GO:0014012	peripheral nervous system axon regeneration	Tspo	IEP		Rat	PMID:8977149\|RGD:2317177
Biological Process	GO:0043065	positive regulation of apoptotic process	Tspo	IMP		Rat	PMID:15284300\|RGD:2317153
Biological Process	GO:0051928	positive regulation of calcium ion transport	Tspo	IMP		Rat	PMID:17174393\|RGD:2317146
Biological Process	GO:0060252	positive regulation of glial cell proliferation	Tspo	IDA		Rat	PMID:18190798\|RGD:2317142
Biological Process	GO:0051901	positive regulation of mitochondrial depolarization	Tspo	IDA		Rat	PMID:15183124\|RGD:2317155
Biological Process	GO:0010940	positive regulation of necrotic cell death	Tspo	IMP		Rat	PMID:15284300\|RGD:2317153
Biological Process	GO:2000379	positive regulation of reactive oxygen species metabolic process	Tspo	IMP		Mouse	MGI:MGI:5689082\|PMID:25470454
Biological Process	GO:2000379	positive regulation of reactive oxygen species metabolic process	Tspo	IDA		Rat	PMID:12437594\|RGD:2317161
Biological Process	GO:0060319	primitive erythrocyte differentiation	tspo	IMP	ZFIN:ZDB-MRPHLNO-100113-1	Zfish	PMID:19723704
Biological Process	GO:0050810	regulation of steroid biosynthetic process	Tspo	IMP		Rat	PMID:9974124\|RGD:2317173
Biological Process	GO:1905144	response to acetylcholine	Tspo	IMP		Rat	PMID:29074640\|RGD:150429771
Biological Process	GO:0048678	response to axon injury	Tspo	IEP		Rat	PMID:15255978\|RGD:2317154
Biological Process	GO:0010042	response to manganese ion	Tspo	IEP		Rat	PMID:12946575\|RGD:2317159
Biological Process	GO:0048265	response to pain	Tspo	IEP		Rat	PMID:19555675\|RGD:2317138
Biological Process	GO:0032570	response to progesterone	Tspo	IEP		Rat	PMID:8201845\|RGD:2317193
Biological Process	GO:0033574	response to testosterone	Tspo	IEP		Rat	PMID:8201845\|RGD:2317193
Biological Process	GO:0010266	response to vitamin B1	Tspo	IEP		Rat	PMID:10517697\|RGD:2317171
Biological Process	GO:0009410	response to xenobiotic stimulus	Tspo	IEP		Rat	PMID:17561380\|RGD:2317143
Biological Process	GO:0006694	steroid biosynthetic process	Tspo	IMP		Rat	PMID:9405411\|RGD:2317176

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/09/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.