Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TTF1
  • Mouse genes Ttf1
  • Rat genes Ttf1
  • Zfish genes ttf1.1,ttf1.2,ttf1.6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ttf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Ttf1	IDA		Mouse	PMID:9049305
Molecular Function	GO:0003677	DNA binding	Ttf1	IDA		Mouse	PMID:7720715
Molecular Function	GO:0003677	DNA binding	Ttf1	IDA		Mouse	PMID:9049305
Molecular Function	GO:0005515	protein binding	TTF1	IPI	UniProtKB:Q96C12	Human	PMID:28169274
Molecular Function	GO:0005515	protein binding	Ttf1	IPI	UniProtKB:Q91YE5	Mouse	MGI:MGI:3852588|PMID:19578370
Molecular Function	GO:0005515	protein binding	Ttf1	IPI	UniProtKB:O54724	Mouse	MGI:MGI:5806011|PMID:27528195
Molecular Function	GO:0005515	protein binding	Ttf1	IPI	PR:Q91YE5	Mouse	PMID:11532953
Cellular Component	GO:0001650	fibrillar center	TTF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Ttf1	IDA		Mouse	PMID:7720715
Biological Process	GO:0006338	chromatin remodeling	Ttf1	IDA		Mouse	PMID:9049305
Biological Process	GO:0006363	termination of RNA polymerase I transcription	Ttf1	IDA		Mouse	PMID:7720715
Biological Process	GO:0006361	transcription initiation at RNA polymerase I promoter	Ttf1	IDA		Mouse	PMID:7720715

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern