Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TTL
  • Mouse genes Ttl
  • Rat genes Ttl
  • Zfish genes ttl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ttl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004835	tubulin-tyrosine ligase activity	TTL	IMP		Human	PMID:25908662
Molecular Function	GO:0004835	tubulin-tyrosine ligase activity	Ttl	IMP	MGI:MGI:3584264	Mouse	PMID:15899979
Molecular Function	GO:0004835	tubulin-tyrosine ligase activity	Ttl	IDA		Rat	PMID:9108330|RGD:634442
Cellular Component	GO:0005876	spindle microtubule	TTL	IDA		Human	PMID:25908662
Biological Process	GO:0000226	microtubule cytoskeleton organization	Ttl	IMP	MGI:MGI:3584264	Mouse	PMID:15899979
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	TTL	IMP		Human	PMID:25908662
Biological Process	GO:0043687	post-translational protein modification	TTL	IMP		Human	PMID:25908662
Biological Process	GO:0030516	regulation of axon extension	Ttl	IMP	MGI:MGI:3584264	Mouse	PMID:15899979
Biological Process	GO:0090235	regulation of metaphase plate congression	TTL	IMP		Human	PMID:25908662

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern