Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TTLL6
  • Mouse genes Ttll6
  • Rat genes Ttll6
  • Zfish genes ttll6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ttll6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TTLL6	IPI	UniProtKB:Q9BYV8	Human	PMID:22246503
Molecular Function	GO:0005515	protein binding	Ttll6	IPI	UniProtKB:Q8C6L5	Mouse	MGI:MGI:5770179|PMID:26829768
Molecular Function	GO:0070739	protein-glutamic acid ligase activity	Ttll6	IDA		Mouse	MGI:MGI:5770179|PMID:26829768
Molecular Function	GO:0070739	protein-glutamic acid ligase activity	Ttll6	IDA		Mouse	MGI:MGI:6479192|PMID:32747782
Molecular Function	GO:0015631	tubulin binding	Ttll6	IDA		Mouse	MGI:MGI:4849873|PMID:21074048
Molecular Function	GO:0070740	tubulin-glutamic acid ligase activity	Ttll6	IDA		Mouse	MGI:MGI:6479192|PMID:32747782
Molecular Function	GO:0070740	tubulin-glutamic acid ligase activity	Ttll6	IDA		Mouse	MGI:MGI:4849873|PMID:21074048
Molecular Function	GO:0070740	tubulin-glutamic acid ligase activity	Ttll6	IDA		Mouse	MGI:MGI:4819643|PMID:20530212
Molecular Function	GO:0070740	tubulin-glutamic acid ligase activity	Ttll6	IDA		Mouse	MGI:MGI:3771321|PMID:17499049
Molecular Function	GO:0070740	tubulin-glutamic acid ligase activity	ttll6	IMP	ZFIN:ZDB-MRPHLNO-110628-7	Zfish	PMID:21262966
Cellular Component	GO:0097731	9+0 non-motile cilium	Ttll6	IDA		Mouse	PMID:17499049
Cellular Component	GO:0036064	ciliary basal body	TTLL6	IDA		Human	PMID:22246503
Cellular Component	GO:0036064	ciliary basal body	Ttll6	IDA		Mouse	PMID:17499049
Cellular Component	GO:0005929	cilium	ttll6	IDA		Zfish	PMID:21262966
Biological Process	GO:0035082	axoneme assembly	ttll6	IMP	ZFIN:ZDB-MRPHLNO-080107-1	Zfish	PMID:17761526
Biological Process	GO:0035082	axoneme assembly	ttll6	IGI	ZFIN:ZDB-MRPHLNO-110628-6,ZFIN:ZDB-MRPHLNO-110628-7	Zfish	PMID:21262966
Biological Process	GO:0035082	axoneme assembly	ttll6	IMP	ZFIN:ZDB-MRPHLNO-110628-7	Zfish	PMID:22246503
Biological Process	GO:0003341	cilium movement	ttll6	IGI	ZFIN:ZDB-MRPHLNO-110628-6,ZFIN:ZDB-MRPHLNO-110628-7	Zfish	PMID:21262966
Biological Process	GO:0001578	microtubule bundle formation	Ttll6	IGI	MGI:MGI:1344353	Mouse	PMID:20530212
Biological Process	GO:0051013	microtubule severing	Ttll6	IGI	MGI:MGI:1858896	Mouse	PMID:20530212
Biological Process	GO:0051013	microtubule severing	Ttll6	IGI	MGI:MGI:1344353	Mouse	PMID:20530212
Biological Process	GO:0051013	microtubule severing	Ttll6	IDA		Mouse	PMID:20530212
Biological Process	GO:0003353	positive regulation of cilium movement	Ttll6	IMP		Mouse	PMID:23897886
Biological Process	GO:0018095	protein polyglutamylation	Ttll6	IDA		Mouse	MGI:MGI:4849873|PMID:21074048
Biological Process	GO:0018095	protein polyglutamylation	Ttll6	IDA		Mouse	MGI:MGI:5770179|PMID:26829768
Biological Process	GO:0018095	protein polyglutamylation	Ttll6	IDA		Mouse	PMID:20530212
Biological Process	GO:0018095	protein polyglutamylation	ttll6	IMP		Zfish	PMID:22246503|ZFIN:ZDB-PUB-120117-22
Biological Process	GO:0060296	regulation of cilium beat frequency involved in ciliary motility	Ttll6	IDA		Mouse	MGI:MGI:5514489|PMID:23897886

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern