Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TTPA
  • Mouse genes Ttpa
  • Rat genes Ttpa
  • Zfish genes ttpa
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ttpa

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0120013	lipid transfer activity	Ttpa	IDA		Mouse	MGI:MGI:5494336|PMID:23599266
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	Ttpa	IDA		Mouse	MGI:MGI:5494336|PMID:23599266
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	Ttpa	IDA		Mouse	MGI:MGI:5494336|PMID:23599266
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q96DZ9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:A8MZ59	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:B3EWG5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:O00623	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:O15126	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:O43761	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:O95182	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:P02655	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:P0DPK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:P53365	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:P55327-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:P59991	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:P60328	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:P60409	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q02127	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q5T9G4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q6IN84	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q6Q788	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q6RW13-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q6ZPD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q7Z769	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q8IZR5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q8N3Y7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q8N5K1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q8N9I5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q8NBQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q8TAC2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q8TAC9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q8WY91	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q92915-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q969L2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q96CA5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q96DZ9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q9BRK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q9BYR9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q9NR31	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q9NRY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q9NS64	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q9NZJ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q9Y680	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TTPA	IPI	UniProtKB:Q9Y371	Human	PMID:32814053
Molecular Function	GO:0019842	vitamin binding	Ttpa	IDA		Rat	PMID:8349655|RGD:730016
Molecular Function	GO:0008431	vitamin E binding	Ttpa	IDA		Mouse	MGI:MGI:5494336|PMID:23599266
Molecular Function	GO:0008431	vitamin E binding	Ttpa	IDA		Rat	PMID:1569384|RGD:1600437
Cellular Component	GO:0005829	cytosol	Ttpa	IDA		Rat	PMID:14531858|RGD:1600431
Cellular Component	GO:0005770	late endosome	Ttpa	IDA		Rat	PMID:14531858|RGD:1600431
Biological Process	GO:0007417	central nervous system development	ttpa	IMP	ZFIN:ZDB-MRPHLNO-121129-3	Zfish	PMID:23077608
Biological Process	GO:0043009	chordate embryonic development	ttpa	IMP	ZFIN:ZDB-MRPHLNO-121129-3	Zfish	PMID:23077608
Biological Process	GO:0032502	developmental process	Ttpa	IEP		Rat	PMID:9523032|RGD:1600434
Biological Process	GO:0001892	embryonic placenta development	Ttpa	IMP	MGI:MGI:2386172	Mouse	PMID:16014812
Biological Process	GO:0120009	intermembrane lipid transfer	Ttpa	IDA		Mouse	MGI:MGI:5494336|PMID:23599266
Biological Process	GO:0051452	intracellular pH reduction	Ttpa	IDA		Rat	PMID:22147702|RGD:7247589
Biological Process	GO:1904036	negative regulation of epithelial cell apoptotic process	Ttpa	IDA		Rat	PMID:22147702|RGD:7247589
Biological Process	GO:0090212	negative regulation of establishment of blood-brain barrier	Ttpa	IMP		Mouse	MGI:MGI:4461120|PMID:19923370
Biological Process	GO:0001890	placenta development	Ttpa	IMP	MGI:MGI:2386172	Mouse	PMID:11076932
Biological Process	GO:1900223	positive regulation of amyloid-beta clearance	Ttpa	IMP	MGI:MGI:2386172	Mouse	PMID:26637123
Biological Process	GO:0007584	response to nutrient	Ttpa	IEP		Rat	PMID:9868180|RGD:1600433
Biological Process	GO:0009268	response to pH	Ttpa	IDA		Rat	PMID:14531858|RGD:1600431
Biological Process	GO:0009636	response to toxic substance	Ttpa	IMP		Mouse	MGI:MGI:4461120|PMID:19923370
Biological Process	GO:0042360	vitamin E metabolic process	Ttpa	IMP		Mouse	MGI:MGI:4461120|PMID:19923370
Biological Process	GO:0042360	vitamin E metabolic process	Ttpa	IMP	MGI:MGI:2386172	Mouse	PMID:16014812
Biological Process	GO:0042360	vitamin E metabolic process	Ttpa	IMP	MGI:MGI:2386172	Mouse	PMID:11076932
Biological Process	GO:0042360	vitamin E metabolic process	Ttpa	IMP	MGI:MGI:1932559	Mouse	PMID:11095717
Biological Process	GO:0042360	vitamin E metabolic process	Ttpa	IDA		Rat	PMID:9356467|RGD:1600435
Biological Process	GO:0051180	vitamin transport	Ttpa	IDA		Mouse	MGI:MGI:5494336|PMID:23599266

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern