Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TUBA1A
  • Mouse genes Tuba1a
  • Rat genes Tuba1a
  • Zfish genes tuba1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tuba1a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005525	GTP binding	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:17218254
Molecular Function	GO:0042802	identical protein binding	TUBA1A	IPI	UniProtKB:Q71U36	Human	PMID:29568061
Molecular Function	GO:0042802	identical protein binding	TUBA1A	IPI	UniProtKB:Q71U36	Human	PMID:30274285
Molecular Function	GO:0005515	protein binding	TUBA1A	IPI	UniProtKB:P00533	Human	PMID:15657067
Molecular Function	GO:0005515	protein binding	TUBA1A	IPI	UniProtKB:P30622-2	Human	PMID:17563362
Molecular Function	GO:0005515	protein binding	TUBA1A	IPI	UniProtKB:Q9NQC7	Human	PMID:19893491
Molecular Function	GO:0005515	protein binding	TUBA1A	IPI	UniProtKB:P05412	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	TUBA1A	IPI	UniProtKB:P10636-8	Human	PMID:21339331
Molecular Function	GO:0005515	protein binding	TUBA1A	IPI	UniProtKB:P00533	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	TUBA1A	IPI	UniProtKB:P00533	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	TUBA1A	IPI	UniProtKB:P05412	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	TUBA1A	IPI	UniProtKB:P07437	Human	PMID:30274285
Molecular Function	GO:0005515	protein binding	TUBA1A	IPI	UniProtKB:P10636-8	Human	PMID:30274285
Molecular Function	GO:0005515	protein binding	TUBA1A	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	TUBA1A	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TUBA1A	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Tuba1a	IPI	UniProtKB:Q80TQ2	Mouse	MGI:MGI:4820954|PMID:19893491
Molecular Function	GO:0005515	protein binding	Tuba1a	IPI	UniProtKB:Q9Z2V5	Mouse	PMID:20037577
Molecular Function	GO:0005515	protein binding	Tuba1a	IPI	UniProtKB:O09106	Mouse	PMID:20037577
Molecular Function	GO:0005515	protein binding	Tuba1a	IPI	UniProtKB:P97358	Mouse	PMID:24244602
Molecular Function	GO:0005515	protein binding	Tuba1a	IPI	UniProtKB:Q15049	Rat	PMID:19931615|RGD:2326037
Molecular Function	GO:0019904	protein domain specific binding	Tuba1a	IDA		Rat	PMID:12750376|RGD:737666
Molecular Function	GO:0046982	protein heterodimerization activity	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:17218254
Molecular Function	GO:0044877	protein-containing complex binding	Tuba1a	IDA		Mouse	PMID:19056362
Cellular Component	GO:0000793	condensed chromosome	Tuba1a	IDA		Mouse	PMID:24244602
Cellular Component	GO:0005881	cytoplasmic microtubule	Tuba1a	IDA		Mouse	PMID:17686994
Cellular Component	GO:0005881	cytoplasmic microtubule	Tuba1a	IDA		Mouse	PMID:19103752
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	TUBA1A	IDA		Human	PMID:15121898
Cellular Component	GO:0005829	cytosol	Tuba1a	IDA		Mouse	PMID:19056362
Cellular Component	GO:0070062	extracellular exosome	TUBA1A	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	TUBA1A	HDA		Human	PMID:19199708
Cellular Component	GO:0045121	membrane raft	Tuba1a	IDA		Rat	PMID:14499952|RGD:12793007
Cellular Component	GO:0005874	microtubule	TUBA1A	IDA		Human	PMID:21525035
Cellular Component	GO:0015630	microtubule cytoskeleton	TUBA1A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043209	myelin sheath	Tuba1a	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0043209	myelin sheath	Tuba1a	IDA		Rat	PMID:17960831|RGD:10047364
Cellular Component	GO:0031594	neuromuscular junction	Tuba1a	IMP		Mouse	PMID:26658218
Cellular Component	GO:0031594	neuromuscular junction	Tuba1a	IDA		Mouse	PMID:26658218
Cellular Component	GO:0005634	nucleus	TUBA1A	HDA		Human	PMID:21630459
Cellular Component	GO:0005886	plasma membrane	Tuba1a	IDA		Mouse	PMID:19056362
Cellular Component	GO:0055037	recycling endosome	TUBA1A	IDA		Human	PMID:24561039
Cellular Component	GO:0045202	synapse	Tuba1a	IDA		Mouse	PMID:19056362
Biological Process	GO:0030534	adult behavior	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:17218254
Biological Process	GO:0008344	adult locomotory behavior	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:17218254
Biological Process	GO:0071277	cellular response to calcium ion	Tuba1a	IDA		Mouse	PMID:27793670
Biological Process	GO:0007098	centrosome cycle	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:28687665
Biological Process	GO:0021696	cerebellar cortex morphogenesis	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:17218254
Biological Process	GO:0021987	cerebral cortex development	Tuba1a	IMP	MGI:MGI:6506267	Mouse	PMID:31386652
Biological Process	GO:0021542	dentate gyrus development	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:21041996
Biological Process	GO:0048853	forebrain morphogenesis	Tuba1a	IMP	MGI:MGI:6506267	Mouse	PMID:31386652
Biological Process	GO:0010467	gene expression	Tuba1a	IMP		Mouse	PMID:31386652
Biological Process	GO:0010001	glial cell differentiation	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:28687665
Biological Process	GO:0021766	hippocampus development	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:17218254
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:21875651
Biological Process	GO:0006886	intracellular protein transport	Tuba1a	IMP	MGI:MGI:5925400	Mouse	PMID:32184299
Biological Process	GO:0007613	memory	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:17218254
Biological Process	GO:0000226	microtubule cytoskeleton organization	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:21875651
Biological Process	GO:0000226	microtubule cytoskeleton organization	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:28687665
Biological Process	GO:0046785	microtubule polymerization	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:28687665
Biological Process	GO:0046785	microtubule polymerization	Tuba1a	IMP	MGI:MGI:5925400	Mouse	PMID:32184299
Biological Process	GO:0061744	motor behavior	Tuba1a	IMP	MGI:MGI:5925400	Mouse	PMID:32184299
Biological Process	GO:0043066	negative regulation of apoptotic process	tuba1a	IMP	ZFIN:ZDB-MRPHLNO-100608-4	Zfish	PMID:20123021
Biological Process	GO:0043066	negative regulation of apoptotic process	tuba1a	IMP	ZFIN:ZDB-MRPHLNO-100608-3	Zfish	PMID:20123021
Biological Process	GO:0022008	neurogenesis	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:21041996
Biological Process	GO:0022008	neurogenesis	Tuba1a	IMP	MGI:MGI:6506267	Mouse	PMID:31386652
Biological Process	GO:0051402	neuron apoptotic process	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:21875651
Biological Process	GO:0030182	neuron differentiation	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:28687665
Biological Process	GO:0001764	neuron migration	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:17218254
Biological Process	GO:0001764	neuron migration	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:21875651
Biological Process	GO:0001764	neuron migration	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:21041996
Biological Process	GO:0001764	neuron migration	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:28687665
Biological Process	GO:0001764	neuron migration	Tuba1a	IMP	MGI:MGI:6506267	Mouse	PMID:31386652
Biological Process	GO:0140058	neuron projection arborization	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:28687665
Biological Process	GO:0021634	optic nerve formation	tuba1a	IMP	ZFIN:ZDB-MRPHLNO-100608-3	Zfish	PMID:20123021
Biological Process	GO:0021634	optic nerve formation	tuba1a	IMP	ZFIN:ZDB-MRPHLNO-100608-4	Zfish	PMID:20123021
Biological Process	GO:0072384	organelle transport along microtubule	Tuba1a	IMP	MGI:MGI:5925400	Mouse	PMID:32184299
Biological Process	GO:0050807	regulation of synapse organization	Tuba1a	IDA		Mouse	PMID:26658218
Biological Process	GO:0050807	regulation of synapse organization	Tuba1a	IMP		Mouse	PMID:26658218
Biological Process	GO:1902065	response to L-glutamate	Tuba1a	IDA		Mouse	PMID:20037577
Biological Process	GO:0009612	response to mechanical stimulus	Tuba1a	IMP		Mouse	PMID:27976998
Biological Process	GO:0034612	response to tumor necrosis factor	Tuba1a	IDA		Mouse	PMID:20037577
Biological Process	GO:0007224	smoothened signaling pathway	Tuba1a	IDA		Mouse	PMID:27793670
Biological Process	GO:0001964	startle response	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:21875651
Biological Process	GO:0050808	synapse organization	Tuba1a	IMP	MGI:MGI:5925400	Mouse	PMID:32184299
Biological Process	GO:0008542	visual learning	Tuba1a	IMP	MGI:MGI:3617352	Mouse	PMID:17218254

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern