Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TUBA1B
  • Mouse genes Tuba1b
  • Rat genes Tuba1b
  • Zfish genes tuba1b,tuba1c
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tuba1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003725	double-stranded RNA binding	TUBA1B	IDA		Human	PMID:21266579
Molecular Function	GO:0005525	GTP binding	TUBA1B	IDA		Human	PMID:34996871
Molecular Function	GO:0003924	GTPase activity	TUBA1B	IDA		Human	PMID:34996871
Molecular Function	GO:0005515	protein binding	TUBA1B	IPI	UniProtKB:P37840	Human	PMID:11698390
Molecular Function	GO:0005515	protein binding	TUBA1B	IPI	UniProtKB:Q8AZK7	Human	PMID:18457437
Molecular Function	GO:0005515	protein binding	TUBA1B	IPI	UniProtKB:Q13509	Human	PMID:24021646
Molecular Function	GO:0005515	protein binding	TUBA1B	IPI	UniProtKB:Q6RW13	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TUBA1B	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TUBA1B	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Tuba1b	IPI	UniProtKB:Q9UBP0	Mouse	MGI:MGI:5430892|PMID:17389232
Molecular Function	GO:0005515	protein binding	Tuba1b	IPI	PR:Q9ESD7	Mouse	PMID:20405035
Molecular Function	GO:0005515	protein binding	Tuba1b	IPI	PR:Q65Z93	Mouse	PMID:34354145
Molecular Function	GO:0005200	structural constituent of cytoskeleton	TUBA1B	IDA		Human	PMID:34996871
Molecular Function	GO:0031625	ubiquitin protein ligase binding	TUBA1B	IPI	UniProtKB:O60260	Human	PMID:21753002
Cellular Component	GO:0005881	cytoplasmic microtubule	Tuba1b	IDA		Mouse	PMID:19103752
Cellular Component	GO:0045121	membrane raft	Tuba1b	IDA		Rat	PMID:14499952|RGD:12793007
Cellular Component	GO:0005874	microtubule	TUBA1B	IDA		Human	PMID:21525035
Cellular Component	GO:0015630	microtubule cytoskeleton	TUBA1B	IDA		Human	PMID:34996871
Cellular Component	GO:0015630	microtubule cytoskeleton	TUBA1B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043209	myelin sheath	Tuba1b	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Biological Process	GO:0071353	cellular response to interleukin-4	Tuba1b	IDA		Mouse	PMID:9798653
Biological Process	GO:0000226	microtubule cytoskeleton organization	TUBA1B	IDA		Human	PMID:34996871

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern