Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TUBB1
  • Mouse genes Tubb1
  • Rat genes Tubb1
  • Zfish genes tubb1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tubb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005200	structural constituent of cytoskeleton	Tubb1	IDA		Mouse	PMID:15121885
Cellular Component	GO:0005737	cytoplasm	TUBB1	IDA		Human	PMID:18849486
Cellular Component	GO:0070062	extracellular exosome	TUBB1	HDA		Human	PMID:23533145
Cellular Component	GO:0045171	intercellular bridge	TUBB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005874	microtubule	Tubb1	IDA		Mouse	PMID:18347012
Cellular Component	GO:0015630	microtubule cytoskeleton	TUBB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0072686	mitotic spindle	TUBB1	IDA		Human	GO_REF:0000052
Biological Process	GO:0046785	microtubule polymerization	Tubb1	IMP		Mouse	PMID:30446499
Biological Process	GO:0007017	microtubule-based process	Tubb1	IDA		Mouse	PMID:15121885
Biological Process	GO:0070527	platelet aggregation	Tubb1	IMP		Mouse	PMID:30446499
Biological Process	GO:0030220	platelet formation	Tubb1	IMP		Mouse	PMID:30446499
Biological Process	GO:0051225	spindle assembly	Tubb1	IDA		Mouse	PMID:15121885
Biological Process	GO:0030878	thyroid gland development	Tubb1	IMP		Mouse	PMID:30446499
Biological Process	GO:0070327	thyroid hormone transport	Tubb1	IMP		Mouse	PMID:30446499

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern