Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TUBB3
  • Mouse genes Tubb3
  • Rat genes Tubb3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tubb3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005525	GTP binding	TUBB3	IDA		Human	PMID:34996871
Molecular Function	GO:1990890	netrin receptor binding	TUBB3	IPI	UniProtKB:O95185	Human	PMID:28483977
Molecular Function	GO:1990890	netrin receptor binding	Tubb3	IPI	UniProtKB:O08747	Mouse	MGI:MGI:5906064|PMID:28483977
Molecular Function	GO:0042277	peptide binding	Tubb3	IPI	RGD:71030	Rat	PMID:16893427|RGD:2312776
Molecular Function	GO:0005515	protein binding	TUBB3	IPI	UniProtKB:P54274	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TUBB3	IPI	UniProtKB:P68363	Human	PMID:24021646
Molecular Function	GO:0005515	protein binding	TUBB3	IPI	UniProtKB:P59047	Human	PMID:24374158
Molecular Function	GO:0005515	protein binding	TUBB3	IPI	UniProtKB:O95185	Human	PMID:28483977
Molecular Function	GO:0005515	protein binding	Tubb3	IPI	UniProtKB:Q9UBP0	Mouse	MGI:MGI:5430892|PMID:17389232
Molecular Function	GO:0005515	protein binding	Tubb3	IPI	UniProtKB:O08747	Mouse	MGI:MGI:5906064|PMID:28483977
Molecular Function	GO:0005515	protein binding	Tubb3	IPI	PR:P47757-2	Mouse	PMID:19806181
Molecular Function	GO:0005200	structural constituent of cytoskeleton	TUBB3	IDA		Human	PMID:34996871
Cellular Component	GO:0030424	axon	Tubb3	IDA		Mouse	MGI:MGI:6148385|PMID:28426968
Cellular Component	GO:0030424	axon	Tubb3	IDA		Mouse	PMID:18076286
Cellular Component	GO:0030424	axon	Tubb3	IDA		Mouse	PMID:17761882
Cellular Component	GO:0030424	axon	Tubb3	IDA		Mouse	PMID:22949634
Cellular Component	GO:0030424	axon	Tubb3	IDA		Mouse	PMID:18614158
Cellular Component	GO:0030424	axon	Tubb3	IDA		Mouse	PMID:23434913
Cellular Component	GO:0030424	axon	Tubb3	IDA		Mouse	PMID:15255972
Cellular Component	GO:0030424	axon	Tubb3	IDA		Rat	PMID:12368262|RGD:10047140
Cellular Component	GO:0071944	cell periphery	Tubb3	IDA		Mouse	PMID:24378336
Cellular Component	GO:0005737	cytoplasm	Tubb3	IDA		Mouse	PMID:23090999
Cellular Component	GO:0005737	cytoplasm	Tubb3	IDA		Mouse	PMID:25433207
Cellular Component	GO:0005737	cytoplasm	Tubb3	IDA		Mouse	PMID:22949634
Cellular Component	GO:0005737	cytoplasm	Tubb3	IDA		Mouse	PMID:19389377
Cellular Component	GO:0005737	cytoplasm	Tubb3	IDA		Mouse	PMID:19036983
Cellular Component	GO:0030425	dendrite	Tubb3	IDA		Mouse	MGI:MGI:5553024|PMID:24464040
Cellular Component	GO:0070062	extracellular exosome	TUBB3	HDA		Human	PMID:23533145
Cellular Component	GO:0030175	filopodium	Tubb3	IDA		Mouse	MGI:MGI:5906064|PMID:28483977
Cellular Component	GO:0030426	growth cone	Tubb3	IDA		Mouse	MGI:MGI:5906064|PMID:28483977
Cellular Component	GO:0045171	intercellular bridge	TUBB3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005622	intracellular anatomical structure	Tubb3	IDA		Mouse	PMID:16892058
Cellular Component	GO:0030027	lamellipodium	Tubb3	IDA		Mouse	MGI:MGI:5906064|PMID:28483977
Cellular Component	GO:0005874	microtubule	TUBB3	IDA		Human	PMID:21525035
Cellular Component	GO:0015630	microtubule cytoskeleton	TUBB3	IDA		Human	PMID:34996871
Cellular Component	GO:0015630	microtubule cytoskeleton	TUBB3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0015630	microtubule cytoskeleton	Tubb3	IDA		Mouse	PMID:15003631
Cellular Component	GO:0072686	mitotic spindle	TUBB3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043025	neuronal cell body	Tubb3	IDA		Mouse	PMID:23284756
Cellular Component	GO:0005634	nucleus	TUBB3	HDA		Human	PMID:21630459
Biological Process	GO:0007411	axon guidance	TUBB3	IMP		Human	PMID:20074521
Biological Process	GO:0007411	axon guidance	Tubb3	IMP		Mouse	MGI:MGI:4441021|PMID:20074521
Biological Process	GO:0007411	axon guidance	Tubb3	IMP		Mouse	MGI:MGI:5906064|PMID:28483977
Biological Process	GO:1990791	dorsal root ganglion development	TUBB3	IDA		Human	PMID:28483977
Biological Process	GO:0000226	microtubule cytoskeleton organization	TUBB3	IDA		Human	PMID:34996871
Biological Process	GO:0000278	mitotic cell cycle	Tubb3	IMP		Rat	PMID:12234689|RGD:1334485
Biological Process	GO:0038007	netrin-activated signaling pathway	Tubb3	IMP		Mouse	MGI:MGI:5906064|PMID:28483977
Biological Process	GO:0030182	neuron differentiation	Tubb3	IMP		Rat	PMID:12234689|RGD:1334485

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern