Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TUBB
  • Mouse genes Tubb5
  • Rat genes Tubb5
  • Zfish genes tubb5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tubb5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0032794	GTPase activating protein binding	Tubb5	IPI	RGD:621665	Rat	PMID:16820281|RGD:7207368
Molecular Function	GO:0042288	MHC class I protein binding	TUBB	IDA		Human	PMID:11120798
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:P05067	Human	PMID:16049941
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:Q8AZK7	Human	PMID:18457437
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:P05412	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:Q9BSI4	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:Q15843	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:P51114	Human	PMID:21653829
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:Q5S007	Human	PMID:24275654
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:O14737	Human	PMID:24375412
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:P48643	Human	PMID:24375412
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:Q5S007	Human	PMID:24947832
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:P05412	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:Q71U36	Human	PMID:30274285
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:Q5S007	Human	PMID:31046837
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:I6L9F6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:P00441	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:P19404	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:P27797	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:P36957	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:Q03403	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:Q13501	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:Q15843	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TUBB	IPI	UniProtKB:Q8TDX7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Tubb5	IPI	RGD:731741	Rat	PMID:18220421|RGD:2317194
Molecular Function	GO:0019904	protein domain specific binding	Tubb5	IPI	RGD:621665	Rat	PMID:16820281|RGD:7207368
Molecular Function	GO:0044877	protein-containing complex binding	Tubb5	IDA		Rat	PMID:18220421|RGD:2317194
Molecular Function	GO:0005200	structural constituent of cytoskeleton	Tubb5	IDA		Mouse	PMID:15121885
Molecular Function	GO:0031625	ubiquitin protein ligase binding	TUBB	IPI	UniProtKB:O60260	Human	PMID:21753002
Cellular Component	GO:0044297	cell body	TUBB	IDA		Human	PMID:19567321
Cellular Component	GO:0005737	cytoplasm	TUBB	IDA		Human	PMID:23178297
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	TUBB	IDA		Human	PMID:15121898
Cellular Component	GO:0070062	extracellular exosome	TUBB	HDA		Human	PMID:12519789
Cellular Component	GO:0070062	extracellular exosome	TUBB	HDA		Human	PMID:21362503
Cellular Component	GO:0070062	extracellular exosome	TUBB	HDA		Human	PMID:23533145
Cellular Component	GO:0045171	intercellular bridge	TUBB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045121	membrane raft	Tubb5	IDA		Rat	PMID:14499952|RGD:12793007
Cellular Component	GO:0005874	microtubule	TUBB	IDA		Human	PMID:21525035
Cellular Component	GO:0005874	microtubule	Tubb5	IDA		Mouse	PMID:15121885
Cellular Component	GO:0015630	microtubule cytoskeleton	TUBB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0072686	mitotic spindle	TUBB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005641	nuclear envelope lumen	TUBB	IDA		Human	PMID:19567321
Cellular Component	GO:0005634	nucleus	TUBB	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	Tubb5	IDA		Mouse	PMID:18480465
Cellular Component	GO:0032991	protein-containing complex	Tubb5	IDA		Rat	PMID:18220421|RGD:2317194
Biological Process	GO:0048484	enteric nervous system development	tubb5	IGI	ZFIN:ZDB-CRISPR-230208-6,ZFIN:ZDB-MRPHLNO-081020-2	Zfish	PMID:34358225
Biological Process	GO:0031101	fin regeneration	tubb5	IMP	ZFIN:ZDB-MRPHLNO-160627-2	Zfish	PMID:26933814
Biological Process	GO:0007017	microtubule-based process	Tubb5	IDA		Mouse	PMID:15121885
Biological Process	GO:0071895	odontoblast differentiation	TUBB	IDA		Human	PMID:19567321
Biological Process	GO:0050807	regulation of synapse organization	Tubb5	IDA		Mouse	PMID:24833723
Biological Process	GO:0050807	regulation of synapse organization	Tubb5	IMP		Mouse	PMID:24833723
Biological Process	GO:0051225	spindle assembly	Tubb5	IDA		Mouse	PMID:15121885

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern