Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TUT4
  • Mouse genes Tut4
  • Rat genes Tut4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tut4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035198	miRNA binding	Tut4	IDA		Mouse	MGI:MGI:6162440|PMID:28671666
Molecular Function	GO:0005515	protein binding	TUT4	IPI	UniProtKB:Q6ZN17	Human	PMID:19703396
Molecular Function	GO:0005515	protein binding	TUT4	IPI	UniProtKB:Q9H9Z2	Human	PMID:19703396
Molecular Function	GO:0005515	protein binding	TUT4	IPI	UniProtKB:Q9HCE1	Human	PMID:30122351
Molecular Function	GO:0005515	protein binding	Tut4	IPI	UniProtKB:Q8K3Y3	Mouse	MGI:MGI:6162440|PMID:28671666
Molecular Function	GO:0005515	protein binding	Tut4	IPI	UniProtKB:Q96CG3	Mouse	PMID:16643855
Molecular Function	GO:0003723	RNA binding	TUT4	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	TUT4	HDA		Human	PMID:22681889
Molecular Function	GO:0050265	RNA uridylyltransferase activity	TUT4	IDA		Human	PMID:19703396
Molecular Function	GO:0050265	RNA uridylyltransferase activity	TUT4	IDA		Human	PMID:25979828
Molecular Function	GO:0050265	RNA uridylyltransferase activity	TUT4	IDA		Human	PMID:35797480
Molecular Function	GO:0050265	RNA uridylyltransferase activity	Tut4	IDA		Mouse	MGI:MGI:4365679|PMID:19701194
Molecular Function	GO:0050265	RNA uridylyltransferase activity	Tut4	IDA		Mouse	MGI:MGI:6162440|PMID:28671666
Molecular Function	GO:0070569	uridylyltransferase activity	Tut4	IDA		Mouse	MGI:MGI:6162440|PMID:28671666
Molecular Function	GO:0070569	uridylyltransferase activity	Tut4	IMP		Mouse	MGI:MGI:6162305|PMID:28792939
Cellular Component	GO:0005737	cytoplasm	TUT4	IDA		Human	PMID:19703396
Cellular Component	GO:0005737	cytoplasm	Tut4	IDA		Mouse	PMID:16643855
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	TUT4	IDA		Human	PMID:30122351
Cellular Component	GO:0005829	cytosol	TUT4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	TUT4	HDA		Human	PMID:19056867
Cellular Component	GO:0005615	extracellular space	TUT4	HDA		Human	PMID:22664934
Cellular Component	GO:0005730	nucleolus	TUT4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Tut4	IDA		Mouse	PMID:16643855
Biological Process	GO:0001816	cytokine production	Tut4	IDA		Mouse	PMID:16643855
Biological Process	GO:0070102	interleukin-6-mediated signaling pathway	Tut4	IMP		Mouse	MGI:MGI:4365679|PMID:19701194
Biological Process	GO:0010587	miRNA catabolic process	TUT4	IMP		Human	PMID:19703396
Biological Process	GO:0010586	miRNA metabolic process	TUT4	IDA		Human	PMID:25979828
Biological Process	GO:0010586	miRNA metabolic process	Tut4	IMP		Mouse	MGI:MGI:4365679|PMID:19701194
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	Tut4	IDA		Mouse	PMID:16643855
Biological Process	GO:0001556	oocyte maturation	Tut4	IMP		Mouse	MGI:MGI:6162305|PMID:28792939
Biological Process	GO:1990074	polyuridylation-dependent mRNA catabolic process	Tut4	IMP		Mouse	MGI:MGI:6162305|PMID:28792939
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Tut4	IMP		Mouse	MGI:MGI:4365679|PMID:19701194
Biological Process	GO:0031054	pre-miRNA processing	TUT4	IMP		Human	PMID:19703396
Biological Process	GO:0031054	pre-miRNA processing	TUT4	IDA		Human	PMID:25979828
Biological Process	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	Tut4	IDA		Mouse	PMID:16643855
Biological Process	GO:0010526	retrotransposon silencing	TUT4	IDA		Human	PMID:30122351
Biological Process	GO:0071076	RNA 3' uridylation	Tut4	IDA		Mouse	MGI:MGI:6162440|PMID:28671666
Biological Process	GO:0071076	RNA 3' uridylation	Tut4	IMP		Mouse	MGI:MGI:6162305|PMID:28792939
Biological Process	GO:0031123	RNA 3'-end processing	TUT4	IDA		Human	PMID:19703396
Biological Process	GO:0031123	RNA 3'-end processing	Tut4	IDA		Mouse	MGI:MGI:4365679|PMID:19701194
Biological Process	GO:0019827	stem cell population maintenance	TUT4	IMP		Human	PMID:19703396

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern