Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TWNK
  • Mouse genes Twnk
  • Rat genes Twnk
  • Zfish genes twnk
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Twnk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043139	5'-3' DNA helicase activity	TWNK	IDA		Human	PMID:12975372
Molecular Function	GO:0043139	5'-3' DNA helicase activity	TWNK	IDA		Human	PMID:15167897
Molecular Function	GO:0043139	5'-3' DNA helicase activity	TWNK	IDA		Human	PMID:18971204
Molecular Function	GO:0003678	DNA helicase activity	Twnk	IDA		Mouse	PMID:11431692
Molecular Function	GO:0042802	identical protein binding	TWNK	IPI	UniProtKB:Q96RR1	Human	PMID:18971204
Molecular Function	GO:0002020	protease binding	TWNK	IPI	UniProtKB:P36776	Human	PMID:14739292
Molecular Function	GO:0003697	single-stranded DNA binding	TWNK	IDA		Human	PMID:18971204
Cellular Component	GO:0042645	mitochondrial nucleoid	TWNK	IDA		Human	PMID:18063578
Cellular Component	GO:0042645	mitochondrial nucleoid	TWNK	IDA		Human	PMID:18971204
Cellular Component	GO:0005739	mitochondrion	Twnk	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Twnk	IDA		Mouse	PMID:11431692
Cellular Component	GO:0005739	mitochondrion	Twnk	IDA		Rat	PMID:22743328|RGD:8694093
Biological Process	GO:0071333	cellular response to glucose stimulus	Twnk	IEP		Rat	PMID:22743328|RGD:8694093
Biological Process	GO:0006268	DNA unwinding involved in DNA replication	TWNK	IDA		Human	PMID:15167897
Biological Process	GO:0006268	DNA unwinding involved in DNA replication	Twnk	IDA		Mouse	PMID:11431692
Biological Process	GO:0006264	mitochondrial DNA replication	TWNK	IMP		Human	PMID:18971204
Biological Process	GO:0006264	mitochondrial DNA replication	Twnk	IMP		Mouse	MGI:MGI:3826298|PMID:18971204
Biological Process	GO:0006390	mitochondrial transcription	TWNK	IMP		Human	PMID:18971204
Biological Process	GO:0034214	protein hexamerization	TWNK	IDA		Human	PMID:18971204

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern