Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TXK
  • Mouse genes Txk
  • Rat genes Txk
  • Zfish genes txk
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Txk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:P09874	Human	PMID:17177976
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:P68104	Human	PMID:17177976
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:P10721	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:O14543	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:O14544	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:O43639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:O60496	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:O75564-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:P27986-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:P46108	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:P62993	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:Q13322-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:Q13422-7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:Q16828	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:Q3KQV3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:Q5JST6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:Q8IZW8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:Q8NA61-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:Q96SQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:Q9GZV8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:Q9H2S9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:Q9NYW8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:Q9UGK3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TXK	IPI	UniProtKB:Q9Y2P0	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	TXK	IDA		Human	PMID:10523612
Cellular Component	GO:0005737	cytoplasm	TXK	IDA		Human	PMID:17177976
Cellular Component	GO:0005829	cytosol	TXK	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	TXK	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	TXK	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TXK	IDA		Human	PMID:10523612
Cellular Component	GO:0005634	nucleus	TXK	IDA		Human	PMID:17177976
Cellular Component	GO:0005886	plasma membrane	TXK	IDA		Human	GO_REF:0000052
Biological Process	GO:0007202	activation of phospholipase C activity	Txk	IMP		Mouse	MGI:MGI:1335923|PMID:10213685
Biological Process	GO:0002250	adaptive immune response	Txk	IMP		Mouse	MGI:MGI:1335923|PMID:10213685
Biological Process	GO:0032633	interleukin-4 production	Txk	IGI	MGI:MGI:96621	Mouse	PMID:18292523
Biological Process	GO:0001865	NK T cell differentiation	Txk	IGI	MGI:MGI:96621	Mouse	PMID:18292523
Biological Process	GO:0001819	positive regulation of cytokine production	Txk	IMP		Mouse	MGI:MGI:1335923|PMID:10213685
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	TXK	IDA		Human	PMID:11859127
Biological Process	GO:0032729	positive regulation of type II interferon production	TXK	IDA		Human	PMID:10523612
Biological Process	GO:0032729	positive regulation of type II interferon production	TXK	IDA		Human	PMID:11859127
Biological Process	GO:0060335	positive regulation of type II interferon-mediated signaling pathway	TXK	IDA		Human	PMID:11859127
Biological Process	GO:0046777	protein autophosphorylation	TXK	IDA		Human	PMID:12081135
Biological Process	GO:0046777	protein autophosphorylation	TXK	IDA		Human	PMID:17177976
Biological Process	GO:0006468	protein phosphorylation	TXK	IDA		Human	PMID:17177976
Biological Process	GO:0010468	regulation of gene expression	TXK	IDA		Human	PMID:11859127
Biological Process	GO:0050852	T cell receptor signaling pathway	Txk	IMP		Mouse	MGI:MGI:1335923|PMID:10213685
Biological Process	GO:0032609	type II interferon production	Txk	IGI	MGI:MGI:96621	Mouse	PMID:18292523

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern