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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Txndc12

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Txndc12
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0005515protein bindingTXNDC12IPIUniProtKB:O43765HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingTXNDC12IPIUniProtKB:O95198HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingTXNDC12IPIUniProtKB:Q96EQ0HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingTXNDC12IPIUniProtKB:Q9UMX0HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingTXNDC12IPIUniProtKB:Q9UMX0-2HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingTXNDC12IPIUniProtKB:O95198HumanPMID:31515488
Molecular FunctionGO:0005515protein bindingTXNDC12IPIUniProtKB:Q9UMX0HumanPMID:31515488
Molecular FunctionGO:0005515protein bindingTXNDC12IPIUniProtKB:P49069HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingTXNDC12IPIUniProtKB:Q92785HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingTXNDC12IPIUniProtKB:Q96EQ0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingTXNDC12IPIUniProtKB:Q9UHD9HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingTXNDC12IPIUniProtKB:Q9Y680HumanPMID:32296183
Molecular FunctionGO:0019153protein-disulfide reductase (glutathione) activityTXNDC12IDAHumanPMID:12761212
Molecular FunctionGO:0047134protein-disulfide reductase (NAD(P)) activitytxndc12IDAZfishPMID:30359749
Molecular FunctionGO:0015035protein-disulfide reductase activityTXNDC12IDAHumanPMID:18628206
Cellular ComponentGO:0005783endoplasmic reticulumTxndc12IDAMousePMID:18628206
Cellular ComponentGO:0005788endoplasmic reticulum lumenTXNDC12IDAHumanPMID:18628206
Cellular ComponentGO:0005788endoplasmic reticulum lumenTXNDC12IDAHumanPMID:12761212
Cellular ComponentGO:0005788endoplasmic reticulum lumenTxndc12IDAMouseMGI:MGI:3688339|PMID:12930873
Cellular ComponentGO:0005788endoplasmic reticulum lumenTxndc12IDARatPMID:12930873|RGD:151356646
Biological ProcessGO:0061691detoxification of hydrogen peroxidetxndc12IDAZfishPMID:30359749
Biological ProcessGO:0006974DNA damage responsetxndc12IDAZfishPMID:30359749
Biological ProcessGO:1902236negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathwayTXNDC12IDAHumanPMID:18628206

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory