Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TXNDC5
  • Mouse genes Txndc5
  • Rat genes Txndc5
  • Zfish genes txndc5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Txndc5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TXNDC5	IPI	UniProtKB:Q13162	Human	PMID:21057456
Molecular Function	GO:0005515	protein binding	TXNDC5	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0003756	protein disulfide isomerase activity	Txndc5	IGI	UniProtKB:P17967	Mouse	MGI:MGI:3688339|PMID:12930873
Molecular Function	GO:0015035	protein-disulfide reductase activity	Txndc5	IDA		Mouse	MGI:MGI:3027402|PMID:14971039
Cellular Component	GO:0005788	endoplasmic reticulum lumen	Txndc5	IDA		Mouse	MGI:MGI:3688339|PMID:12930873
Cellular Component	GO:0070062	extracellular exosome	TXNDC5	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	TXNDC5	HDA		Human	PMID:23533145

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern