Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TXNRD3
  • Mouse genes Txnrd3
  • Rat genes Txnrd3
  • Zfish genes txnrd3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Txnrd3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Txnrd3	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Molecular Function	GO:0004791	thioredoxin-disulfide reductase activity	Txnrd3	IDA		Mouse	PMID:11259642
Cellular Component	GO:0005829	cytosol	TXNRD3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	TXNRD3	IDA		Human	GO_REF:0000052
Biological Process	GO:0001825	blastocyst formation	Txnrd3	IMP		Mouse	PMID:27869233
Biological Process	GO:0006749	glutathione metabolic process	Txnrd3	IDA		Mouse	PMID:11259642

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern