Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes U2AF2
  • Mouse genes U2af2
  • Rat genes U2af2
  • Zfish genes u2af2a,u2af2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set U2af2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070742	C2H2 zinc finger domain binding	U2af2	IPI	UniProtKB:P22561	Mouse	MGI:MGI:4418642|PMID:9784496
Molecular Function	GO:0019899	enzyme binding	U2AF2	IPI	UniProtKB:Q6NYC1	Human	PMID:19574390
Molecular Function	GO:0140678	molecular function inhibitor activity	U2AF2	EXP		Human	PMID:32188783
Molecular Function	GO:0030628	pre-mRNA 3'-splice site binding	U2AF2	IDA		Human	PMID:2531895
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q15637	Human	PMID:10449420
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q01081	Human	PMID:11551507
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q15637	Human	PMID:12718882
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:P78362	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q01081	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q15637	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q9NVV9	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q9UHX1	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:P54253	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q8N684	Human	PMID:17024186
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q96I25	Human	PMID:17589525
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:P82979	Human	PMID:18559666
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:P52756	Human	PMID:18951082
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q13573	Human	PMID:20467437
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q6Y7W6	Human	PMID:20696395
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q01081	Human	PMID:21460037
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q13573	Human	PMID:21460037
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q01081	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:P24928	Human	PMID:21536736
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q9UMS4	Human	PMID:21536736
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q01081	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q8IWZ8	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:O43395	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:P09012	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:P98175	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q01081	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q15637	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q8IWX8	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q8IWZ8	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q9UHX1	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:P52756	Human	PMID:22569250
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q15637	Human	PMID:23273425
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:P78362	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:P54274	Human	PMID:24389012
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:P09012	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q01081	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q08117	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q9NVV9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q9UHX1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q9UI36-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:P54253	Human	PMID:25959826
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q15637	Human	PMID:26420826
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:P78362	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q15696	Human	PMID:9237760
Molecular Function	GO:0005515	protein binding	U2AF2	IPI	UniProtKB:Q99590	Human	PMID:9447963
Molecular Function	GO:0005515	protein binding	U2af2	IPI	UniProtKB:Q15637	Mouse	MGI:MGI:5700260|PMID:26420826
Molecular Function	GO:0005515	protein binding	U2af2	IPI	UniProtKB:Q8BGJ9	Mouse	MGI:MGI:3662966|PMID:16819553
Molecular Function	GO:0005515	protein binding	U2af2	IPI	UniProtKB:Q9ERI5	Mouse	MGI:MGI:4940413|PMID:21300889
Molecular Function	GO:0003723	RNA binding	U2AF2	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	U2AF2	HDA		Human	PMID:22681889
Cellular Component	GO:0016607	nuclear speck	U2AF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	U2AF2	IDA		Human	PMID:1824937
Cellular Component	GO:0016607	nuclear speck	U2AF2	IDA		Human	PMID:21984414
Cellular Component	GO:0005634	nucleus	U2AF2	IDA		Human	PMID:1824937
Cellular Component	GO:0005681	spliceosomal complex	U2AF2	IPI		Human	PMID:11551507
Cellular Component	GO:0005681	spliceosomal complex	U2AF2	IPI		Human	PMID:23273425
Cellular Component	GO:0005681	spliceosomal complex	U2AF2	IDA		Human	PMID:9731529
Cellular Component	GO:0071004	U2-type prespliceosome	U2AF2	IDA		Human	PMID:2531895
Cellular Component	GO:0089701	U2AF complex	U2AF2	IPI		Human	PMID:11551507
Cellular Component	GO:0089701	U2AF complex	U2AF2	IPI		Human	PMID:23273425
Cellular Component	GO:0089701	U2AF complex	U2AF2	IDA		Human	PMID:1824937
Cellular Component	GO:0089701	U2AF complex	U2AF2	IDA		Human	PMID:2531895
Biological Process	GO:0000398	mRNA splicing, via spliceosome	U2AF2	IDA		Human	PMID:1824937
Biological Process	GO:0048025	negative regulation of mRNA splicing, via spliceosome	U2AF2	IDA		Human	PMID:15009664
Biological Process	GO:0031397	negative regulation of protein ubiquitination	U2AF2	IDA		Human	PMID:24389012
Biological Process	GO:0031397	negative regulation of protein ubiquitination	U2AF2	IMP		Human	PMID:24389012
Biological Process	GO:0033120	positive regulation of RNA splicing	U2AF2	IDA		Human	PMID:21536736
Biological Process	GO:0008380	RNA splicing	U2af2	IDA		Mouse	MGI:MGI:4418642|PMID:9784496

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern