Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UACA
  • Mouse genes Uaca
  • Rat genes Uaca
  • Zfish genes uacaa,uacab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Uaca

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	UACA	IPI	UniProtKB:Q9NWT6	Human	PMID:17003112
Molecular Function	GO:0005515	protein binding	UACA	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UACA	IPI	UniProtKB:O43865	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UACA	IPI	UniProtKB:P31321	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UACA	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UACA	IPI	UniProtKB:Q5QGT7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UACA	IPI	UniProtKB:Q86Z20	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UACA	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Uaca	IPI	UniProtKB:Q8BHC1|UniProtKB:Q8BHD0	Mouse	MGI:MGI:5644013|PMID:23624502
Molecular Function	GO:0005515	protein binding	Uaca	IPI	UniProtKB:P17931	Mouse	PMID:14961764
Molecular Function	GO:0005515	protein binding	Uaca	IPI	PR:Q8K419	Mouse	PMID:14961764
Cellular Component	GO:0043293	apoptosome	Uaca	IDA		Mouse	PMID:15271982
Cellular Component	GO:0005737	cytoplasm	Uaca	IDA		Mouse	PMID:14961764
Cellular Component	GO:0005737	cytoplasm	Uaca	IDA		Mouse	PMID:12761289
Cellular Component	GO:0005829	cytosol	UACA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Uaca	IDA		Mouse	PMID:15271982
Cellular Component	GO:0070062	extracellular exosome	UACA	HDA		Human	PMID:19056867
Cellular Component	GO:0016020	membrane	Uaca	IDA		Mouse	PMID:12761289
Cellular Component	GO:0005635	nuclear envelope	Uaca	IDA		Mouse	PMID:12761289
Cellular Component	GO:0005635	nuclear envelope	Uaca	IDA		Mouse	PMID:14961764
Cellular Component	GO:0005654	nucleoplasm	UACA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Uaca	IDA		Mouse	PMID:15271982
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Uaca	IDA		Mouse	PMID:15271982
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	Uaca	IMP	MGI:MGI:3043446	Mouse	PMID:15271982
Biological Process	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	Uaca	IMP	MGI:MGI:3043446	Mouse	PMID:15271982
Biological Process	GO:0050728	negative regulation of inflammatory response	Uaca	IMP	MGI:MGI:3043446	Mouse	PMID:14961764
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	Uaca	IMP	MGI:MGI:3043446	Mouse	PMID:14961764
Biological Process	GO:0038061	NIK/NF-kappaB signaling	Uaca	IMP	MGI:MGI:3043446	Mouse	PMID:14961764
Biological Process	GO:0043065	positive regulation of apoptotic process	Uaca	IDA		Mouse	PMID:15271982
Biological Process	GO:0043065	positive regulation of apoptotic process	Uaca	IMP	MGI:MGI:3043446	Mouse	PMID:14961764
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Uaca	IMP	MGI:MGI:3043446	Mouse	PMID:15271982
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Uaca	IDA		Mouse	PMID:15271982
Biological Process	GO:0042307	positive regulation of protein import into nucleus	Uaca	IMP	MGI:MGI:3043446	Mouse	PMID:15271982
Biological Process	GO:0006606	protein import into nucleus	Uaca	IMP	MGI:MGI:3043446	Mouse	PMID:15271982
Biological Process	GO:0009411	response to UV	Uaca	IMP	MGI:MGI:3043446	Mouse	PMID:15271982

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern