Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UBE2A
  • Mouse genes Ube2a
  • Rat genes Ube2a
  • Zfish genes ube2a,ube2al
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ube2a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:Q9NS91	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:Q9BTA9	Human	PMID:21329877
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:Q9NS91	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:Q9NS91	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:O14645	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:O14901	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:O75400-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:O75460-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:P06396	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:P13473-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:P28329-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:P30519	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:P41091	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:P54652	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:P55212	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:P62826	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:Q0VDC6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:Q14957	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:Q8WZA2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:Q96CV9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:Q9BVL2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:Q9UMX0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2A	IPI	UniProtKB:Q9Y649	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Ube2a	IPI	PR:Q5U430	Mouse	PMID:17462990
Molecular Function	GO:0005515	protein binding	Ube2a	IPI	PR:P24860	Mouse	PMID:12525704
Molecular Function	GO:0005515	protein binding	Ube2a	IPI	PR:O70481	Mouse	PMID:17462990
Molecular Function	GO:0005515	protein binding	Ube2a	IPI	PR:Q8VH31	Mouse	PMID:12525704
Molecular Function	GO:0005515	protein binding	Ube2a	IPI	PR:Q9QXK2	Mouse	PMID:12509447
Molecular Function	GO:0061631	ubiquitin conjugating enzyme activity	UBE2A	IDA		Human	PMID:20061386
Molecular Function	GO:0061631	ubiquitin conjugating enzyme activity	Ube2a	IGI	MGI:MGI:1861100	Mouse	PMID:17462990
Molecular Function	GO:0031625	ubiquitin protein ligase binding	UBE2A	IPI	UniProtKB:Q9NS91	Human	PMID:10908344
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Ube2a	IDA		Mouse	PMID:17462990
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	UBE2A	IDA		Human	PMID:11953320
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	UBE2A	IDA		Human	PMID:20061386
Cellular Component	GO:0000785	chromatin	Ube2a	IDA		Mouse	PMID:15657431
Cellular Component	GO:0000785	chromatin	Ube2a	IDA		Mouse	PMID:15383616
Cellular Component	GO:0033503	HULC complex	UBE2A	IDA		Human	PMID:19410543
Cellular Component	GO:0001741	XY body	Ube2a	IDA		Mouse	PMID:15383616
Biological Process	GO:0001835	blastocyst hatching	Ube2a	IMP		Mouse	PMID:27869233
Biological Process	GO:0006281	DNA repair	UBE2A	IGI	UniProtKB:P06104	Human	PMID:1717990
Biological Process	GO:0033522	histone H2A ubiquitination	UBE2A	IDA		Human	PMID:11953320
Biological Process	GO:0001701	in utero embryonic development	Ube2a	IGI	MGI:MGI:102944	Mouse	PMID:15169909
Biological Process	GO:0060135	maternal process involved in female pregnancy	Ube2a	IMP	MGI:MGI:2450874	Mouse	PMID:15169909
Biological Process	GO:0008284	positive regulation of cell population proliferation	UBE2A	IDA		Human	PMID:11953320
Biological Process	GO:0051865	protein autoubiquitination	UBE2A	IDA		Human	PMID:11953320
Biological Process	GO:0070979	protein K11-linked ubiquitination	UBE2A	IDA		Human	PMID:20061386
Biological Process	GO:0070936	protein K48-linked ubiquitination	UBE2A	IDA		Human	PMID:20061386
Biological Process	GO:0016567	protein ubiquitination	Ube2a	IDA		Mouse	PMID:25023518
Biological Process	GO:0009411	response to UV	UBE2A	IGI	UniProtKB:P06104	Human	PMID:1717990

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern