Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UBE2B
  • Mouse genes Ube2b
  • Rat genes Ube2b
  • Zfish genes ube2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ube2b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	UBE2B	IPI	UniProtKB:Q9UBW7	Human	PMID:12776193
Molecular Function	GO:0005515	protein binding	UBE2B	IPI	UniProtKB:Q8IWV7	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	UBE2B	IPI	UniProtKB:Q9NS91	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	UBE2B	IPI	UniProtKB:Q7L7L0	Human	PMID:20080676
Molecular Function	GO:0005515	protein binding	UBE2B	IPI	UniProtKB:Q8IWV7	Human	PMID:21422291
Molecular Function	GO:0005515	protein binding	UBE2B	IPI	UniProtKB:Q9NS91	Human	PMID:21422291
Molecular Function	GO:0005515	protein binding	UBE2B	IPI	UniProtKB:Q9NS91	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	UBE2B	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2B	IPI	UniProtKB:Q9BSE4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ube2b	IPI	PR:Q9QXK2	Mouse	PMID:12509447
Molecular Function	GO:0005515	protein binding	Ube2b	IPI	PR:O70481	Mouse	PMID:17462990
Molecular Function	GO:0005515	protein binding	Ube2b	IPI	PR:Q5U430	Mouse	PMID:17462990
Molecular Function	GO:0005515	protein binding	Ube2b	IPI	PR:Q6WKZ8	Mouse	PMID:14585983
Molecular Function	GO:0061631	ubiquitin conjugating enzyme activity	Ube2b	IGI	MGI:MGI:1861099	Mouse	PMID:14585983
Molecular Function	GO:0061631	ubiquitin conjugating enzyme activity	Ube2b	IGI	MGI:MGI:1861100	Mouse	PMID:17462990
Molecular Function	GO:0031625	ubiquitin protein ligase binding	UBE2B	IPI	UniProtKB:Q9NS91	Human	PMID:10908344
Molecular Function	GO:0031625	ubiquitin protein ligase binding	UBE2B	IPI	UniProtKB:Q9NS91	Human	PMID:18363965
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Ube2b	IDA		Mouse	PMID:14585983
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Ube2b	IDA		Mouse	PMID:17462990
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	UBE2B	IDA		Human	PMID:10373550
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	UBE2B	IMP		Human	PMID:18339854
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	UBE2B	IDA		Human	PMID:19123975
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	UBE2B	IDA		Human	PMID:20061386
Cellular Component	GO:0000785	chromatin	Ube2b	IDA		Mouse	PMID:15383616
Cellular Component	GO:0000785	chromatin	Ube2b	IDA		Mouse	PMID:15657431
Cellular Component	GO:0005737	cytoplasm	UBE2B	IDA		Human	PMID:18339854
Cellular Component	GO:0033503	HULC complex	UBE2B	IDA		Human	PMID:19410543
Cellular Component	GO:0005634	nucleus	UBE2B	IDA		Human	PMID:18339854
Cellular Component	GO:0005657	replication fork	UBE2B	IDA		Human	PMID:18363965
Cellular Component	GO:0001741	XY body	Ube2b	IDA		Mouse	PMID:15383616
Biological Process	GO:0006915	apoptotic process	Ube2b	IMP	MGI:MGI:2183933	Mouse	PMID:12556476
Biological Process	GO:0032869	cellular response to insulin stimulus	Ube2b	IEP		Rat	PMID:8048511|RGD:1299378
Biological Process	GO:0051026	chiasma assembly	Ube2b	IMP	MGI:MGI:2183933	Mouse	PMID:12556476
Biological Process	GO:0006325	chromatin organization	Ube2b	IMP	MGI:MGI:2183933	Mouse	PMID:17488778
Biological Process	GO:0006974	DNA damage response	UBE2B	IDA		Human	PMID:14981545
Biological Process	GO:0006281	DNA repair	UBE2B	IGI	UniProtKB:P06104	Human	PMID:1717990
Biological Process	GO:0035234	ectopic germ cell programmed cell death	Ube2b	IMP	MGI:MGI:2183933	Mouse	PMID:12556476
Biological Process	GO:0033522	histone H2A ubiquitination	UBE2B	IMP		Human	PMID:18339854
Biological Process	GO:0001701	in utero embryonic development	Ube2b	IGI	MGI:MGI:102959	Mouse	PMID:15169909
Biological Process	GO:0000237	leptotene	Ube2b	IMP	MGI:MGI:2183933	Mouse	PMID:17010969
Biological Process	GO:0045141	meiotic telomere clustering	Ube2b	IMP	MGI:MGI:2183933	Mouse	PMID:17010969
Biological Process	GO:0043066	negative regulation of apoptotic process	Ube2b	IMP	MGI:MGI:2183933	Mouse	PMID:12556476
Biological Process	GO:0043951	negative regulation of cAMP-mediated signaling	UBE2B	IDA		Human	PMID:10373550
Biological Process	GO:0051093	negative regulation of developmental process	Ube2b	IMP	MGI:MGI:2183933	Mouse	PMID:12556476
Biological Process	GO:1901874	negative regulation of post-translational protein modification	Ube2b	IMP	MGI:MGI:2183933	Mouse	PMID:17488778
Biological Process	GO:2000242	negative regulation of reproductive process	Ube2b	IMP	MGI:MGI:2183933	Mouse	PMID:12556476
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	Ube2b	IMP		Mouse	MGI:MGI:3852303|PMID:18339854
Biological Process	GO:0010845	positive regulation of reciprocal meiotic recombination	Ube2b	IMP	MGI:MGI:2183933	Mouse	PMID:12556476
Biological Process	GO:0006301	postreplication repair	UBE2B	IDA		Human	PMID:14981545
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	UBE2B	IDA		Human	PMID:10373550
Biological Process	GO:0051865	protein autoubiquitination	UBE2B	IDA		Human	PMID:19123975
Biological Process	GO:0070979	protein K11-linked ubiquitination	UBE2B	IDA		Human	PMID:20061386
Biological Process	GO:0070936	protein K48-linked ubiquitination	UBE2B	IDA		Human	PMID:20061386
Biological Process	GO:0070534	protein K63-linked ubiquitination	UBE2B	IDA		Human	PMID:20061386
Biological Process	GO:0006513	protein monoubiquitination	UBE2B	IMP		Human	PMID:18339854
Biological Process	GO:0000209	protein polyubiquitination	UBE2B	IMP		Human	PMID:18339854
Biological Process	GO:0050821	protein stabilization	UBE2B	IMP		Human	PMID:18339854
Biological Process	GO:0016567	protein ubiquitination	UBE2B	IDA		Human	PMID:10373550
Biological Process	GO:0016567	protein ubiquitination	UBE2B	IDA		Human	PMID:19123975
Biological Process	GO:0001666	response to hypoxia	Ube2b	IEP		Rat	PMID:16483544|RGD:2308869
Biological Process	GO:0009411	response to UV	UBE2B	IGI	UniProtKB:P06104	Human	PMID:1717990
Biological Process	GO:0009410	response to xenobiotic stimulus	UBE2B	IDA		Human	PMID:14981545
Biological Process	GO:0007288	sperm axoneme assembly	Ube2b	IMP	MGI:MGI:2183933	Mouse	PMID:12672659
Biological Process	GO:0070193	synaptonemal complex organization	Ube2b	IMP	MGI:MGI:2183933	Mouse	PMID:17488778
Biological Process	GO:0070193	synaptonemal complex organization	Ube2b	IMP	MGI:MGI:2183933	Mouse	PMID:12556476
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	UBE2B	IDA		Human	PMID:10373550
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Ube2b	IEP		Rat	PMID:8048511|RGD:1299378

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern