Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UBE2K
  • Mouse genes Ube2k
  • Rat genes Ube2k
  • Zfish genes ube2ka,ube2kb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ube2k

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q8IUQ4	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q8WVD3	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:P14635	Human	PMID:20965177
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:P42858	Human	PMID:23275563
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q99PZ6	Human	PMID:24446487
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q04864	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q8IUQ4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q8N9I9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q8TD10	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q8WTU0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q8WVD3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q99942	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9HCM9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:P14373	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q8WVD3	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:O00522	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:O15344	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:P14373	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:P24863	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:P26367	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q06587	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q15024	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q15631	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q86XT4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q8N6D2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q8N9I9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q8TD10	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q8WVD3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q96A37	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q96D59	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q96GF1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q99942	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9BZY9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9C035-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9H992	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9HCM9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9NZS9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9UJV3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9UPQ4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:A0A024RCP2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:O15273	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:O60506-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:P09936	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:P14373	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:P40337-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:P62879	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q06587	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q12888	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q13064	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q15843	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q4G1C9-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q6DHV7-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q6IAA8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q6PIA0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q6ZNA4-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q7L8L6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q86UD3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q8IUQ4-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q8TDB6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q8WUW1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q8WUY3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q8WVD3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q96BD6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q96BQ3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q96CA5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q96GL9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q96LI6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q99496	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q99619	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q99942	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9BWF2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9BYM8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9BYM8-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9BZY9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9C035-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9C040	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9H0A6-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9H270	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9H4P4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9H6Y7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9HCM9-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9NX09	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9NZS9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9ULV8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9UPQ4-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9UQM7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9Y3D0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBE2K	IPI	UniProtKB:Q9Y508	Human	PMID:32814053
Molecular Function	GO:0031625	ubiquitin protein ligase binding	UBE2K	IPI	UniProtKB:Q1L721	Human	PMID:16714285
Molecular Function	GO:0031625	ubiquitin protein ligase binding	UBE2K	IPI	UniProtKB:P38398	Human	PMID:17873885
Molecular Function	GO:0031625	ubiquitin protein ligase binding	UBE2K	IPI	UniProtKB:Q9H992	Human	PMID:18410486
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	UBE2K	IDA		Human	PMID:20061386
Molecular Function	GO:0034450	ubiquitin-ubiquitin ligase activity	UBE2K	IDA		Human	PMID:17873885
Cellular Component	GO:0005737	cytoplasm	Ube2k	IDA		Mouse	PMID:18511602
Cellular Component	GO:0032433	filopodium tip	Ube2k	IDA		Mouse	PMID:18511602
Cellular Component	GO:0005634	nucleus	Ube2k	IDA		Mouse	PMID:18511602
Biological Process	GO:0035458	cellular response to interferon-beta	UBE2K	IMP		Human	PMID:24882218
Biological Process	GO:0010994	free ubiquitin chain polymerization	UBE2K	IDA		Human	PMID:24882218
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Ube2k	IMP		Rat	PMID:18710920|RGD:8554156
Biological Process	GO:0010800	positive regulation of peptidyl-threonine phosphorylation	UBE2K	IDA		Human	PMID:24882218
Biological Process	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway	UBE2K	IMP		Human	PMID:26707646
Biological Process	GO:0060340	positive regulation of type I interferon-mediated signaling pathway	UBE2K	IMP		Human	PMID:24882218
Biological Process	GO:0070936	protein K48-linked ubiquitination	UBE2K	IDA		Human	PMID:20061386
Biological Process	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	Ube2k	IDA		Mouse	PMID:18710920

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern