Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UBE4B
  • Mouse genes Ube4b
  • Rat genes Ube4b
  • Zfish genes ube4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ube4b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	Ube4b	IDA		Mouse	PMID:23509263
Molecular Function	GO:0051117	ATPase binding	Ube4b	IPI	UniProtKB:Q01853	Rat	PMID:10811609|RGD:633500
Molecular Function	GO:0019899	enzyme binding	Ube4b	IPI	UniProtKB:Q01853	Mouse	MGI:MGI:2449210|PMID:12504083
Molecular Function	GO:0005515	protein binding	Ube4b	IPI	PR:Q01853	Mouse	PMID:12504083
Molecular Function	GO:0005515	protein binding	Ube4b	IPI	PR:P61079	Mouse	PMID:23509263
Molecular Function	GO:0005515	protein binding	Ube4b	IPI	PR:Q8VDW4	Mouse	PMID:23509263
Molecular Function	GO:0005515	protein binding	Ube4b	IPI	UniProtKB:Q99689	Mouse	PMID:15466860
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Ube4b	IDA		Mouse	PMID:23509263
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Ube4b	IDA		Mouse	PMID:20017557
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Ube4b	IDA		Mouse	PMID:15466860
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Ube4b	IDA		Mouse	PMID:11435423
Molecular Function	GO:0034450	ubiquitin-ubiquitin ligase activity	Ube4b	IDA		Mouse	PMID:11435423
Molecular Function	GO:0034450	ubiquitin-ubiquitin ligase activity	Ube4b	IDA		Mouse	PMID:20017557
Cellular Component	GO:0005737	cytoplasm	Ube4b	IDA		Mouse	MGI:MGI:2449210|PMID:12504083
Cellular Component	GO:0005634	nucleus	Ube4b	IDA		Mouse	PMID:11435423
Biological Process	GO:0008626	granzyme-mediated apoptotic signaling pathway	UBE4B	IDA		Human	PMID:11802788
Biological Process	GO:0031175	neuron projection development	Ube4b	IMP	MGI:MGI:3611069	Mouse	PMID:16314518
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	UBE4B	IDA		Human	PMID:23509263
Biological Process	GO:0051865	protein autoubiquitination	Ube4b	IDA		Mouse	PMID:23509263
Biological Process	GO:0030163	protein catabolic process	Ube4b	IMP	MGI:MGI:3611069	Mouse	PMID:16314518
Biological Process	GO:0006513	protein monoubiquitination	Ube4b	IDA		Mouse	PMID:23509263
Biological Process	GO:0000209	protein polyubiquitination	Ube4b	IDA		Mouse	PMID:23509263
Biological Process	GO:0000209	protein polyubiquitination	Ube4b	IMP	MGI:MGI:3611069	Mouse	PMID:16314518
Biological Process	GO:0000209	protein polyubiquitination	Ube4b	IDA		Mouse	PMID:11435423
Biological Process	GO:0016567	protein ubiquitination	Ube4b	IDA		Mouse	PMID:15466860
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Ube4b	IMP	MGI:MGI:3611069	Mouse	PMID:16314518
Biological Process	GO:0009411	response to UV	UBE4B	IDA		Human	PMID:11802788
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Ube4b	IMP	MGI:MGI:3611069	Mouse	PMID:16314518
Biological Process	GO:0003222	ventricular trabecula myocardium morphogenesis	Ube4b	IMP	MGI:MGI:3611069	Mouse	PMID:16314518

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern