Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UCHL3
  • Mouse genes Uchl4
  • Rat genes Uchl3
  • Zfish genes uchl3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Uchl4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	UCHL3	IDA		Human	PMID:19047059
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	UCHL3	EXP		Human	PMID:26235645
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	UCHL3	IDA		Human	PMID:9521656
Molecular Function	GO:0008233	peptidase activity	UCHL3	IDA		Human	PMID:21762696
Molecular Function	GO:0005515	protein binding	UCHL3	IPI	UniProtKB:Q15797	Human	PMID:21453705
Molecular Function	GO:0005515	protein binding	UCHL3	IPI	UniProtKB:G5E9A7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UCHL3	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0043130	ubiquitin binding	UCHL3	IDA		Human	PMID:19154770
Cellular Component	GO:0005829	cytosol	UCHL3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	UCHL3	IDA		Human	GO_REF:0000052
Biological Process	GO:1904888	cranial skeletal system development	uchl3	IMP	ZFIN:ZDB-MRPHLNO-100225-31	Zfish	PMID:28450118
Biological Process	GO:0007219	Notch signaling pathway	uchl3	IMP	ZFIN:ZDB-MRPHLNO-100225-31	Zfish	PMID:20040115
Biological Process	GO:0030163	protein catabolic process	UCHL3	IDA		Human	PMID:21762696
Biological Process	GO:0016579	protein deubiquitination	UCHL3	IDA		Human	PMID:19047059
Biological Process	GO:0016579	protein deubiquitination	UCHL3	IDA		Human	PMID:9521656

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern