Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UCN
  • Mouse genes Ucn
  • Rat genes Ucn
  • Zfish genes uts1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ucn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051430	corticotropin-releasing hormone receptor 1 binding	Ucn	IPI	RGD:61276	Rat	PMID:15049707|RGD:5490990
Molecular Function	GO:0051431	corticotropin-releasing hormone receptor 2 binding	Ucn	IPI	RGD:70547	Rat	PMID:7477349|RGD:70047
Molecular Function	GO:0001664	G protein-coupled receptor binding	Ucn	IDA		Rat	PMID:11784785|RGD:70397
Molecular Function	GO:0046811	histone deacetylase inhibitor activity	Ucn	IDA		Rat	PMID:19875195|RGD:5508309
Molecular Function	GO:0005515	protein binding	UCN	IPI	UniProtKB:P24387	Human	PMID:18234674
Molecular Function	GO:0005515	protein binding	Ucn	IPI	UniProtKB:P35353	Rat	PMID:24290358|RGD:8554713
Molecular Function	GO:0005515	protein binding	Ucn	IPI	RGD:730851	Rat	PMID:7477349|RGD:70047
Cellular Component	GO:0030424	axon	Ucn	IDA		Rat	PMID:12379245|RGD:1642792
Cellular Component	GO:0043679	axon terminus	Ucn	IDA		Rat	PMID:12379245|RGD:1642792
Cellular Component	GO:0030425	dendrite	Ucn	IDA		Rat	PMID:12379245|RGD:1642792
Cellular Component	GO:0043025	neuronal cell body	Ucn	IDA		Rat	PMID:12379245|RGD:1642792
Cellular Component	GO:0043204	perikaryon	Ucn	IDA		Rat	PMID:10553117|RGD:5491004
Cellular Component	GO:0043196	varicosity	Ucn	IDA		Rat	PMID:15796765|RGD:5508814
Biological Process	GO:0034199	activation of protein kinase A activity	Ucn	IDA		Rat	PMID:19460778|RGD:5508168
Biological Process	GO:0009060	aerobic respiration	Ucn	IDA		Rat	PMID:11597609|RGD:5508185
Biological Process	GO:0008306	associative learning	Ucn	IDA		Rat	PMID:10366634|RGD:5508167
Biological Process	GO:0042756	drinking behavior	Ucn	IMP		Rat	PMID:10751559|RGD:1642799
Biological Process	GO:0007631	feeding behavior	Ucn	IMP		Rat	PMID:10751559|RGD:1642799
Biological Process	GO:0007565	female pregnancy	Ucn	IEP		Rat	PMID:17391780|RGD:1642779
Biological Process	GO:0035483	gastric emptying	Ucn	IDA		Rat	PMID:21540451|RGD:5490560
Biological Process	GO:0006954	inflammatory response	Ucn	IEP		Rat	PMID:16427607|RGD:1642781
Biological Process	GO:0007611	learning or memory	Ucn	IDA		Rat	PMID:12376180|RGD:730151
Biological Process	GO:0043066	negative regulation of apoptotic process	Ucn	IDA		Rat	PMID:14519439|RGD:2306174
Biological Process	GO:0032099	negative regulation of appetite	Ucn	IDA		Rat	PMID:21540451|RGD:5490560
Biological Process	GO:0045776	negative regulation of blood pressure	Ucn	IDA		Rat	PMID:15604589|RGD:1642785
Biological Process	GO:0045792	negative regulation of cell size	Ucn	IDA		Rat	PMID:19460778|RGD:5508168
Biological Process	GO:2000252	negative regulation of feeding behavior	Ucn	IDA		Rat	PMID:11597609|RGD:5508185
Biological Process	GO:0060455	negative regulation of gastric acid secretion	Ucn	IDA		Rat	PMID:21540451|RGD:5490560
Biological Process	GO:0010629	negative regulation of gene expression	Ucn	IDA		Rat	PMID:14563694|RGD:5508192
Biological Process	GO:0010629	negative regulation of gene expression	Ucn	IDA		Rat	PMID:21540451|RGD:5490560
Biological Process	GO:0046888	negative regulation of hormone secretion	Ucn	IDA		Rat	PMID:21540451|RGD:5490560
Biological Process	GO:0060547	negative regulation of necrotic cell death	Ucn	IDA		Rat	PMID:20933497|RGD:5508190
Biological Process	GO:1901215	negative regulation of neuron death	Ucn	IDA		Rat	PMID:11784785|RGD:70397
Biological Process	GO:0031175	neuron projection development	Ucn	IDA		Rat	PMID:15078549|RGD:1642788
Biological Process	GO:0007218	neuropeptide signaling pathway	Ucn	IDA		Rat	PMID:11784785|RGD:70397
Biological Process	GO:0030157	pancreatic juice secretion	Ucn	IDA		Rat	PMID:12895659|RGD:1642798
Biological Process	GO:2000987	positive regulation of behavioral fear response	Ucn	IDA		Rat	PMID:10366634|RGD:5508167
Biological Process	GO:0090280	positive regulation of calcium ion import	Ucn	IDA		Rat	PMID:16513211|RGD:1626238
Biological Process	GO:0090280	positive regulation of calcium ion import	Ucn	IDA		Rat	PMID:19460778|RGD:5508168
Biological Process	GO:0043950	positive regulation of cAMP-mediated signaling	Ucn	IDA		Rat	PMID:7477349|RGD:70047
Biological Process	GO:0060452	positive regulation of cardiac muscle contraction	Ucn	IDA		Rat	PMID:19460778|RGD:5508168
Biological Process	GO:0030307	positive regulation of cell growth	Ucn	IDA		Rat	PMID:15694367|RGD:1642784
Biological Process	GO:0032967	positive regulation of collagen biosynthetic process	Ucn	IDA		Rat	PMID:11087261|RGD:1642796
Biological Process	GO:0051461	positive regulation of corticotropin secretion	UCN	IDA		Human	PMID:11329063
Biological Process	GO:0051461	positive regulation of corticotropin secretion	Ucn	IDA		Rat	PMID:7477349|RGD:70047
Biological Process	GO:0045740	positive regulation of DNA replication	Ucn	IDA		Rat	PMID:11087261|RGD:1642796
Biological Process	GO:0010628	positive regulation of gene expression	Ucn	IDA		Rat	PMID:21540451|RGD:5490560
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Ucn	IDA		Rat	PMID:12746280|RGD:1642791
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	Ucn	IDA		Rat	PMID:19875195|RGD:5508309
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Ucn	IDA		Rat	PMID:14519439|RGD:2306174
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ucn	IMP		Mouse	MGI:MGI:2183706|PMID:12091910
Biological Process	GO:0045727	positive regulation of translation	Ucn	IDA		Rat	PMID:11087261|RGD:1642796
Biological Process	GO:0043117	positive regulation of vascular permeability	Ucn	IDA		Rat	PMID:19819946|RGD:5508179
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	Ucn	IDA		Rat	PMID:15102917|RGD:1642787
Biological Process	GO:0010996	response to auditory stimulus	Ucn	IMP		Mouse	MGI:MGI:2183706|PMID:12091910
Biological Process	GO:0010996	response to auditory stimulus	Ucn	IMP		Mouse	MGI:MGI:2385506|PMID:12192058
Biological Process	GO:0032355	response to estradiol	Ucn	IEP		Rat	PMID:16672665|RGD:1642780
Biological Process	GO:0051384	response to glucocorticoid	Ucn	IEP		Rat	PMID:16427607|RGD:1642781
Biological Process	GO:0006979	response to oxidative stress	Ucn	IDA		Rat	PMID:11784785|RGD:70397
Biological Process	GO:0048265	response to pain	Ucn	IEP		Rat	PMID:21463663|RGD:5490545
Biological Process	GO:0035176	social behavior	Ucn	IDA		Rat	PMID:16488545|RGD:5507822
Biological Process	GO:0001964	startle response	Ucn	IMP		Mouse	MGI:MGI:2385506|PMID:12192058
Biological Process	GO:0042311	vasodilation	Ucn	IDA		Rat	PMID:15467262|RGD:1642786

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern