Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UCN2
  • Mouse genes Ucn2
  • Rat genes Ucn2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ucn2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051431	corticotropin-releasing hormone receptor 2 binding	Ucn2	IPI	RGD:70547	Rat	PMID:19334530|RGD:5130955
Molecular Function	GO:0051429	corticotropin-releasing hormone receptor binding	UCN2	IPI	UniProtKB:Q13324	Human	PMID:11329063
Molecular Function	GO:0001664	G protein-coupled receptor binding	Ucn2	IDA		Mouse	PMID:15514029
Molecular Function	GO:0042562	hormone binding	UCN2	IPI	UniProtKB:Q13324	Human	PMID:11329063
Molecular Function	GO:0005515	protein binding	Ucn2	IPI	PR:Q60748	Mouse	PMID:15514029
Molecular Function	GO:0005515	protein binding	Ucn2	IPI	PR:Q61190	Mouse	PMID:11416224
Cellular Component	GO:0005615	extracellular space	Ucn2	IDA		Rat	PMID:17283244|RGD:2317018
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	UCN2	IDA		Human	PMID:11329063
Biological Process	GO:0008283	cell population proliferation	Ucn2	IDA		Rat	PMID:12175707|RGD:724785
Biological Process	GO:0071385	cellular response to glucocorticoid stimulus	Ucn2	IEP		Rat	PMID:17283244|RGD:2317018
Biological Process	GO:0071456	cellular response to hypoxia	Ucn2	IEP		Rat	PMID:14519439|RGD:2306174
Biological Process	GO:0009755	hormone-mediated signaling pathway	UCN2	IDA		Human	PMID:11329063
Biological Process	GO:0046882	negative regulation of follicle-stimulating hormone secretion	Ucn2	IMP		Rat	PMID:19193717|RGD:2317015
Biological Process	GO:0010629	negative regulation of gene expression	Ucn2	IMP		Rat	PMID:19193717|RGD:2317015
Biological Process	GO:0033685	negative regulation of luteinizing hormone secretion	Ucn2	IMP		Rat	PMID:19193717|RGD:2317015
Biological Process	GO:0035902	response to immobilization stress	Ucn2	IEP		Rat	PMID:12869794|RGD:2317020

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern