Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UCP3
  • Mouse genes Ucp3
  • Rat genes Ucp3
  • Zfish genes ucp3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ucp3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0017077	oxidative phosphorylation uncoupler activity	UCP3	IMP		Human	PMID:21775425
Molecular Function	GO:0017077	oxidative phosphorylation uncoupler activity	UCP3	IDA		Human	PMID:36114012
Molecular Function	GO:0017077	oxidative phosphorylation uncoupler activity	UCP3	IDA		Human	PMID:9305858
Molecular Function	GO:0017077	oxidative phosphorylation uncoupler activity	Ucp3	IMP	MGI:MGI:2183166	Mouse	PMID:10748196
Molecular Function	GO:0017077	oxidative phosphorylation uncoupler activity	Ucp3	IMP	MGI:MGI:2183202	Mouse	PMID:10748195
Molecular Function	GO:0005515	protein binding	UCP3	IPI	UniProtKB:P03495	Human	PMID:24008843
Molecular Function	GO:0005515	protein binding	Ucp3	IPI	UniProtKB:O00165|UniProtKB:O35387	Mouse	MGI:MGI:6880400|PMID:26915802
Molecular Function	GO:0015078	proton transmembrane transporter activity	UCP3	IDA		Human	PMID:11171965
Molecular Function	GO:0015078	proton transmembrane transporter activity	UCP3	IDA		Human	PMID:12670931
Molecular Function	GO:0015078	proton transmembrane transporter activity	Ucp3	IDA		Mouse	MGI:MGI:6884251|PMID:29212043
Cellular Component	GO:0005743	mitochondrial inner membrane	Ucp3	IDA		Mouse	MGI:MGI:6880400|PMID:26915802
Cellular Component	GO:0005739	mitochondrion	Ucp3	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Ucp3	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Ucp3	IMP	MGI:MGI:2183204	Mouse	PMID:11707458
Cellular Component	GO:0005739	mitochondrion	Ucp3	IDA		Rat	PMID:18328500|RGD:2313532
Biological Process	GO:0007568	aging	Ucp3	IEP		Rat	PMID:19526856|RGD:2313527
Biological Process	GO:0032870	cellular response to hormone stimulus	Ucp3	IEP		Rat	PMID:17478558|RGD:2313534
Biological Process	GO:0006631	fatty acid metabolic process	Ucp3	IMP	MGI:MGI:2183166	Mouse	PMID:10748196
Biological Process	GO:1901373	lipid hydroperoxide transport	Ucp3	IMP		Mouse	MGI:MGI:4830072|PMID:20363757
Biological Process	GO:1902600	proton transmembrane transport	UCP3	IDA		Human	PMID:11171965
Biological Process	GO:1902600	proton transmembrane transport	Ucp3	IDA		Mouse	MGI:MGI:6884251|PMID:29212043
Biological Process	GO:0014823	response to activity	Ucp3	IEP		Rat	PMID:18977294|RGD:2313530
Biological Process	GO:0009409	response to cold	Ucp3	IEP		Rat	PMID:9367914|RGD:2313537
Biological Process	GO:0051384	response to glucocorticoid	Ucp3	IEP		Rat	PMID:18591261|RGD:2313531
Biological Process	GO:0001666	response to hypoxia	Ucp3	IDA		Rat	PMID:15292030|RGD:2315862
Biological Process	GO:0001666	response to hypoxia	Ucp3	IEP		Rat	PMID:19082433|RGD:2313529
Biological Process	GO:0032868	response to insulin	Ucp3	IEP		Rat	PMID:10868941|RGD:2313524
Biological Process	GO:0007584	response to nutrient	Ucp3	IEP		Rat	PMID:16962595|RGD:2313536
Biological Process	GO:0048545	response to steroid hormone	Ucp3	IEP		Rat	PMID:12659879|RGD:2313629
Biological Process	GO:0000303	response to superoxide	Ucp3	IMP	MGI:MGI:2183204	Mouse	PMID:11780125
Biological Process	GO:0000303	response to superoxide	Ucp3	IDA		Rat	PMID:11780125|RGD:737664

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern