Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ufd1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes UFD1
- Mouse genes Ufd1
- Rat genes Ufd1
- Zfish genes ufd1l
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ufd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051117	ATPase binding	Ufd1	IPI	UniProtKB:Q01853	Rat	PMID:10811609\|RGD:633500
Molecular Function	GO:0051117	ATPase binding	Ufd1	IPI	UniProtKB:Q01853	Rat	PMID:12847084\|RGD:10047330
Molecular Function	GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	Ufd1	IDA		Mouse	MGI:MGI:5634892\|PMID:12847084
Molecular Function	GO:0005515	protein binding	UFD1	IPI	UniProtKB:Q8TAT6	Human	PMID:11574150
Molecular Function	GO:0005515	protein binding	UFD1	IPI	UniProtKB:Q9UKV5	Human	PMID:17681147
Molecular Function	GO:0005515	protein binding	UFD1	IPI	UniProtKB:P55072	Human	PMID:18775313
Molecular Function	GO:0005515	protein binding	UFD1	IPI	UniProtKB:Q8TAT6	Human	PMID:18775313
Molecular Function	GO:0005515	protein binding	UFD1	IPI	UniProtKB:P55072	Human	PMID:20414249
Molecular Function	GO:0005515	protein binding	UFD1	IPI	UniProtKB:Q8TAT6	Human	PMID:20414249
Molecular Function	GO:0005515	protein binding	UFD1	IPI	UniProtKB:Q8TAT6	Human	PMID:21645854
Molecular Function	GO:0005515	protein binding	UFD1	IPI	UniProtKB:P42858	Human	PMID:25959826
Molecular Function	GO:0005515	protein binding	UFD1	IPI	UniProtKB:P55072	Human	PMID:26712280
Molecular Function	GO:0005515	protein binding	UFD1	IPI	UniProtKB:Q8TAT6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UFD1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Ufd1	IPI	UniProtKB:Q01853\|UniProtKB:Q9ES54	Mouse	MGI:MGI:5914283\|PMID:22232657
Molecular Function	GO:0005515	protein binding	Ufd1	IPI	UniProtKB:Q01853	Mouse	MGI:MGI:5440826\|PMID:22773186
Molecular Function	GO:0005515	protein binding	Ufd1	IPI	UniProtKB:Q01853\|UniProtKB:Q9ES54	Mouse	MGI:MGI:5634894\|PMID:10811609
Molecular Function	GO:0005515	protein binding	Ufd1	IPI	UniProtKB:Q9ES54	Mouse	MGI:MGI:6092812\|PMID:17202270
Molecular Function	GO:0005515	protein binding	Ufd1	IPI	UniProtKB:Q9ES54	Rat	PMID:10811609\|RGD:633500
Molecular Function	GO:0044877	protein-containing complex binding	Ufd1	IPI	RGD:621595\|RGD:620794	Rat	PMID:10811609\|RGD:633500
Molecular Function	GO:0005102	signaling receptor binding	Ufd1	IPI	RGD:2933	Rat	PMID:16103111\|RGD:1599730
Cellular Component	GO:0005737	cytoplasm	Ufd1	IDA		Mouse	PMID:18775783
Cellular Component	GO:0005634	nucleus	UFD1	HDA		Human	PMID:21630459
Cellular Component	GO:0036501	UFD1-NPL4 complex	UFD1	IPI	UniProtKB:Q8TAT6	Human	PMID:11574150
Cellular Component	GO:0036501	UFD1-NPL4 complex	Ufd1	IDA		Mouse	MGI:MGI:5634894\|PMID:10811609
Cellular Component	GO:0036501	UFD1-NPL4 complex	Ufd1	IDA		Rat	PMID:10811609\|RGD:633500
Cellular Component	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	UFD1	IPI		Human	PMID:20414249
Cellular Component	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	UFD1	IDA		Human	PMID:26471729
Cellular Component	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	Ufd1	IDA		Mouse	MGI:MGI:5634894\|PMID:10811609
Cellular Component	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	Ufd1	IDA		Mouse	MGI:MGI:5640950\|PMID:17000876
Cellular Component	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	Ufd1	EXP		Mouse	MGI:MGI:5914283\|PMID:22232657
Cellular Component	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	Ufd1	EXP		Rat	PMID:22232657\|RGD:13432281
Cellular Component	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	Ufd1	IDA		Rat	PMID:10811609\|RGD:633500
Cellular Component	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	Ufd1	IPI	UniProtKB:Q01853	Rat	PMID:12847084\|RGD:10047330
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	ufd1l	IDA		Zfish	PMID:18618001
Biological Process	GO:0048484	enteric nervous system development	ufd1l	IMP	ZFIN:ZDB-CRISPR-230208-10	Zfish	PMID:34358225
Biological Process	GO:0071712	ER-associated misfolded protein catabolic process	UFD1	IMP		Human	PMID:24089527
Biological Process	GO:0039536	negative regulation of RIG-I signaling pathway	UFD1	IMP		Human	PMID:26471729
Biological Process	GO:0032480	negative regulation of type I interferon production	UFD1	IMP		Human	PMID:26471729
Biological Process	GO:0030970	retrograde protein transport, ER to cytosol	UFD1	IMP		Human	PMID:25660456
Biological Process	GO:0030970	retrograde protein transport, ER to cytosol	Ufd1	EXP		Mouse	MGI:MGI:5634892\|PMID:12847084
Biological Process	GO:0030970	retrograde protein transport, ER to cytosol	Ufd1	EXP		Rat	PMID:12847084\|RGD:10047330
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	Ufd1	EXP		Mouse	MGI:MGI:5634892\|PMID:12847084
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	Ufd1	EXP		Rat	PMID:12847084\|RGD:10047330
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	UFD1	IMP		Human	PMID:26471729

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.