Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UFL1
  • Mouse genes Ufl1
  • Rat genes Ufl1
  • Zfish genes ufl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ufl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	UFL1	IPI	UniProtKB:Q96HY6	Human	PMID:20018847
Molecular Function	GO:0005515	protein binding	UFL1	IPI	UniProtKB:Q9Y3C8	Human	PMID:20018847
Molecular Function	GO:0005515	protein binding	UFL1	IPI	UniProtKB:Q04206	Human	PMID:20164180
Molecular Function	GO:0005515	protein binding	UFL1	IPI	UniProtKB:Q96JB5	Human	PMID:20164180
Molecular Function	GO:0005515	protein binding	UFL1	IPI	UniProtKB:Q96JB5	Human	PMID:20228063
Molecular Function	GO:0005515	protein binding	UFL1	IPI	UniProtKB:Q15650	Human	PMID:25219498
Molecular Function	GO:0005515	protein binding	UFL1	IPI	UniProtKB:Q96HY6	Human	PMID:25219498
Molecular Function	GO:0005515	protein binding	UFL1	IPI	UniProtKB:Q9Y3C8	Human	PMID:30886146
Molecular Function	GO:0005515	protein binding	UFL1	IPI	UniProtKB:Q96HY6	Human	PMID:32160526
Molecular Function	GO:0005515	protein binding	UFL1	IPI	UniProtKB:Q96JB5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ufl1	IPI	UniProtKB:Q99LM2	Mouse	MGI:MGI:5613470|PMID:21494687
Molecular Function	GO:0005515	protein binding	Ufl1	IPI	UniProtKB:Q99LM2	Mouse	MGI:MGI:6284072|PMID:30635284
Molecular Function	GO:0019901	protein kinase binding	UFL1	IPI	UniProtKB:Q13315	Human	PMID:30886146
Molecular Function	GO:0061666	UFM1 ligase activity	UFL1	IDA		Human	PMID:20018847
Molecular Function	GO:0061666	UFM1 ligase activity	UFL1	IDA		Human	PMID:30886146
Molecular Function	GO:0061666	UFM1 ligase activity	UFL1	IDA		Human	PMID:32160526
Cellular Component	GO:0005737	cytoplasm	UFL1	IDA		Human	PMID:20164180
Cellular Component	GO:0005737	cytoplasm	UFL1	IDA		Human	PMID:30886146
Cellular Component	GO:0005737	cytoplasm	Ufl1	IDA		Mouse	PMID:20531390
Cellular Component	GO:0005783	endoplasmic reticulum	UFL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	UFL1	IDA		Human	PMID:20018847
Cellular Component	GO:0005783	endoplasmic reticulum	UFL1	IDA		Human	PMID:20531390
Cellular Component	GO:0005789	endoplasmic reticulum membrane	UFL1	IDA		Human	PMID:20531390
Cellular Component	GO:0005789	endoplasmic reticulum membrane	UFL1	IDA		Human	PMID:32160526
Cellular Component	GO:0016020	membrane	UFL1	HDA		Human	PMID:16210410
Cellular Component	GO:0043005	neuron projection	Ufl1	IDA		Mouse	PMID:20531390
Cellular Component	GO:0005634	nucleus	UFL1	IDA		Human	PMID:30886146
Cellular Component	GO:0032991	protein-containing complex	UFL1	IDA		Human	PMID:20531390
Cellular Component	GO:0035861	site of double-strand break	UFL1	IDA		Human	PMID:30886146
Biological Process	GO:0000077	DNA damage checkpoint signaling	UFL1	IDA		Human	PMID:30886146
Biological Process	GO:0030218	erythrocyte differentiation	Ufl1	IMP		Mouse	MGI:MGI:5818653|PMID:25952549
Biological Process	GO:0060218	hematopoietic stem cell differentiation	Ufl1	IMP		Mouse	MGI:MGI:5818653|PMID:25952549
Biological Process	GO:0043066	negative regulation of apoptotic process	Ufl1	IMP		Rat	PMID:21494687|RGD:11567254
Biological Process	GO:1903895	negative regulation of IRE1-mediated unfolded protein response	UFL1	IDA		Human	PMID:32160526
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	UFL1	IMP		Human	PMID:20164180
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	UFL1	IMP		Human	PMID:20228063
Biological Process	GO:0031397	negative regulation of protein ubiquitination	UFL1	IDA		Human	PMID:20164180
Biological Process	GO:0001649	osteoblast differentiation	UFL1	HDA		Human	PMID:16210410
Biological Process	GO:0010508	positive regulation of autophagy	Ufl1	IMP		Mouse	MGI:MGI:5818653|PMID:25952549
Biological Process	GO:0008284	positive regulation of cell population proliferation	UFL1	IMP		Human	PMID:20531390
Biological Process	GO:0060252	positive regulation of glial cell proliferation	Ufl1	IDA		Mouse	PMID:20531390
Biological Process	GO:0060252	positive regulation of glial cell proliferation	Ufl1	IMP		Mouse	PMID:20531390
Biological Process	GO:1990592	protein K69-linked ufmylation	UFL1	IDA		Human	PMID:25219498
Biological Process	GO:0071569	protein ufmylation	UFL1	IMP		Human	PMID:23152784
Biological Process	GO:0071569	protein ufmylation	UFL1	IDA		Human	PMID:20018847
Biological Process	GO:0071569	protein ufmylation	UFL1	IDA		Human	PMID:30886146
Biological Process	GO:0071569	protein ufmylation	UFL1	IDA		Human	PMID:32160526
Biological Process	GO:0010468	regulation of gene expression	Ufl1	IMP		Mouse	PMID:20531390
Biological Process	GO:0033146	regulation of intracellular estrogen receptor signaling pathway	UFL1	IDA		Human	PMID:25219498
Biological Process	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	UFL1	IMP		Human	PMID:20228063
Biological Process	GO:0032880	regulation of protein localization	UFL1	IMP		Human	PMID:20531390
Biological Process	GO:0034976	response to endoplasmic reticulum stress	UFL1	IDA		Human	PMID:23152784
Biological Process	GO:0034976	response to endoplasmic reticulum stress	UFL1	IDA		Human	PMID:32160526
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Ufl1	IMP		Mouse	MGI:MGI:5818653|PMID:25952549
Biological Process	GO:1902065	response to L-glutamate	Ufl1	IMP		Mouse	PMID:20531390
Biological Process	GO:0061709	reticulophagy	UFL1	IDA		Human	PMID:32160526

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern