Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAET1E,ULBP1,ULBP2,ULBP3
  • Mouse genes Ulbp1
  • Rat genes
  • Zfish genes mhc1laa,mhc1lba,mhc1lca,mhc1lga,mhc1lla,si:dkey-52p2.5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ulbp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046703	natural killer cell lectin-like receptor binding	RAET1E	IPI	UniProtKB:P26718	Human	PMID:15240696
Molecular Function	GO:0046703	natural killer cell lectin-like receptor binding	ULBP3	IDA		Human	PMID:11239445
Molecular Function	GO:0046703	natural killer cell lectin-like receptor binding	ULBP2	IDA		Human	PMID:11239445
Molecular Function	GO:0046703	natural killer cell lectin-like receptor binding	ULBP1	IDA		Human	PMID:11239445
Molecular Function	GO:0046703	natural killer cell lectin-like receptor binding	Ulbp1	IPI	PR:O54709	Mouse	PMID:12645935
Molecular Function	GO:0005515	protein binding	RAET1E	IPI	UniProtKB:O54709	Human	PMID:18544572
Molecular Function	GO:0005515	protein binding	RAET1E	IPI	UniProtKB:P26718	Human	PMID:19436053
Molecular Function	GO:0005515	protein binding	RAET1E	IPI	UniProtKB:P26718	Human	PMID:19658097
Molecular Function	GO:0005515	protein binding	RAET1E	IPI	UniProtKB:P26718	Human	PMID:28559451
Molecular Function	GO:0005515	protein binding	ULBP3	IPI	UniProtKB:P26718	Human	PMID:11754823
Molecular Function	GO:0005515	protein binding	ULBP3	IPI	UniProtKB:P26718	Human	PMID:18544572
Molecular Function	GO:0005515	protein binding	ULBP3	IPI	UniProtKB:P26718	Human	PMID:28559451
Molecular Function	GO:0005515	protein binding	ULBP3	IPI	UniProtKB:P01100	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ULBP3	IPI	UniProtKB:P31930	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ULBP2	IPI	UniProtKB:P26718	Human	PMID:19424970
Molecular Function	GO:0005515	protein binding	ULBP2	IPI	UniProtKB:P26718	Human	PMID:28559451
Molecular Function	GO:0005515	protein binding	ULBP2	IPI	UniProtKB:Q96EC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ULBP2	IPI	UniProtKB:Q96Q80	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ULBP1	IPI	UniProtKB:P26718	Human	PMID:28559451
Cellular Component	GO:0009986	cell surface	ULBP2	IDA		Human	PMID:18676862
Cellular Component	GO:0005829	cytosol	ULBP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0009897	external side of plasma membrane	Ulbp1	IDA		Mouse	PMID:12645935
Cellular Component	GO:0005615	extracellular space	ULBP2	IDA		Human	PMID:18676862
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ULBP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ULBP3	IDA		Human	PMID:11239445
Cellular Component	GO:0005886	plasma membrane	ULBP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ULBP2	IDA		Human	PMID:11239445
Cellular Component	GO:0005886	plasma membrane	ULBP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ULBP1	IDA		Human	PMID:11239445
Cellular Component	GO:0005886	plasma membrane	Ulbp1	IDA		Mouse	PMID:12645935
Biological Process	GO:0030101	natural killer cell activation	ULBP3	IDA		Human	PMID:11239445
Biological Process	GO:0030101	natural killer cell activation	ULBP2	IDA		Human	PMID:11239445
Biological Process	GO:0030101	natural killer cell activation	ULBP1	IDA		Human	PMID:11239445
Biological Process	GO:0042267	natural killer cell mediated cytotoxicity	RAET1E	IDA		Human	PMID:15240696
Biological Process	GO:0042267	natural killer cell mediated cytotoxicity	ULBP3	IDA		Human	PMID:11239445
Biological Process	GO:0042267	natural killer cell mediated cytotoxicity	ULBP2	IDA		Human	PMID:11239445
Biological Process	GO:0042267	natural killer cell mediated cytotoxicity	ULBP1	IDA		Human	PMID:11239445
Biological Process	GO:0002839	positive regulation of immune response to tumor cell	Ulbp1	IDA		Mouse	PMID:12645935
Biological Process	GO:0043032	positive regulation of macrophage activation	Ulbp1	IDA		Mouse	PMID:12645935
Biological Process	GO:0032816	positive regulation of natural killer cell activation	Ulbp1	IDA		Mouse	PMID:12645935
Biological Process	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	RAET1E	IDA		Human	PMID:18544572
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	Ulbp1	IDA		Mouse	PMID:12645935
Biological Process	GO:0032729	positive regulation of type II interferon production	Ulbp1	IDA		Mouse	PMID:12645935
Biological Process	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity	Ulbp1	IDA		Mouse	PMID:12645935

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern