Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UNC119
  • Mouse genes Unc119
  • Rat genes Unc119
  • Zfish genes unc119a,unc119b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Unc119

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008289	lipid binding	UNC119	IDA		Human	PMID:21642972
Molecular Function	GO:0008289	lipid binding	UNC119	IDA		Human	PMID:22085962
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:P06239	Human	PMID:14757743
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:P06241	Human	PMID:14757743
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:P36405	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q9NXU5	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q96GX8	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:P36404	Human	PMID:18588884
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:P36405	Human	PMID:18588884
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:P36405	Human	PMID:22085962
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q717R9	Human	PMID:22085962
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q7Z494	Human	PMID:22085962
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q96GV9	Human	PMID:22085962
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q7Z494	Human	PMID:22960633
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q9D0J4	Human	PMID:22960633
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q9WUL7	Human	PMID:22960633
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:P06241	Human	PMID:23535298
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:P62491	Human	PMID:23535298
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:P36404	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q4VCS5-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q96GX8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:P36405	Human	PMID:26455799
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:P36404	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:P36405	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q7Z494	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:P36405	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:O94889	Human	PMID:31696965
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:A2BDD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:P36404	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:P36405	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:P48454	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q08209-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q5T3J3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q6ZRY4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q86VY9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q8IUG1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q96A56	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q96GX8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q9BYQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q9BYQ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q9NXU5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UNC119	IPI	UniProtKB:Q9UKA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Unc119	IPI	UniProtKB:Q05193	Mouse	MGI:MGI:5559669|PMID:19781630
Molecular Function	GO:0005515	protein binding	Unc119	IPI	UniProtKB:E9Q4F2|UniProtKB:P48453|UniProtKB:P48455|UniProtKB:P63328	Mouse	MGI:MGI:6383261|PMID:31696965
Molecular Function	GO:0005515	protein binding	Unc119	IPI	PR:Q7TNH6	Mouse	PMID:29395339
Molecular Function	GO:0005515	protein binding	Unc119	IPI	UniProtKB:O08697	Rat	PMID:12527357|RGD:8553320
Cellular Component	GO:0005813	centrosome	UNC119	IDA		Human	PMID:22085962
Cellular Component	GO:0005813	centrosome	UNC119	IDA		Human	PMID:23535298
Cellular Component	GO:0045171	intercellular bridge	UNC119	IDA		Human	PMID:23535298
Cellular Component	GO:0051233	spindle midzone	UNC119	IDA		Human	PMID:23535298
Cellular Component	GO:0000922	spindle pole	UNC119	IDA		Human	PMID:23535298
Biological Process	GO:0070121	Kupffer's vesicle development	unc119b	IMP	ZFIN:ZDB-MRPHLNO-120424-5	Zfish	PMID:22085962
Biological Process	GO:0042953	lipoprotein transport	UNC119	IDA		Human	PMID:21642972
Biological Process	GO:0042953	lipoprotein transport	UNC119	IDA		Human	PMID:22085962
Biological Process	GO:0042953	lipoprotein transport	Unc119	IMP		Mouse	MGI:MGI:5050777|PMID:21642972
Biological Process	GO:0000281	mitotic cytokinesis	UNC119	IMP		Human	PMID:23535298
Biological Process	GO:2001287	negative regulation of caveolin-mediated endocytosis	Unc119	IMP		Mouse	MGI:MGI:5559669|PMID:19781630
Biological Process	GO:1900186	negative regulation of clathrin-dependent endocytosis	Unc119	IMP		Mouse	MGI:MGI:5559669|PMID:19781630
Biological Process	GO:0061098	positive regulation of protein tyrosine kinase activity	UNC119	IMP		Human	PMID:14757743
Biological Process	GO:0007601	visual perception	unc119b	IMP	ZFIN:ZDB-MRPHLNO-120424-5	Zfish	PMID:22085962

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern