Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Unc13b

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes UNC13B
- Mouse genes Unc13b
- Rat genes Unc13b
- Zfish genes unc13bb
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Unc13b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005516	calmodulin binding	Unc13b	IDA		Rat	PMID:19492809\|RGD:11535108
Molecular Function	GO:0005516	calmodulin binding	Unc13b	IDA		Rat	PMID:22966208\|RGD:11535109
Molecular Function	GO:0030742	GTP-dependent protein binding	UNC13B	IPI	UniProtKB:Q9BZG1	Human	PMID:16138900
Molecular Function	GO:0005515	protein binding	UNC13B	IPI	UniProtKB:Q9BZG1	Human	PMID:16138900
Molecular Function	GO:0005515	protein binding	Unc13b	IPI	UniProtKB:Q9JIR4	Rat	PMID:11343654\|RGD:634478
Molecular Function	GO:0005515	protein binding	Unc13b	IPI	UniProtKB:Q9JIR4	Rat	PMID:21262469\|RGD:10047275
Molecular Function	GO:0019905	syntaxin binding	Unc13b	IDA		Rat	PMID:9895278\|RGD:11535093
Molecular Function	GO:0017075	syntaxin-1 binding	Unc13b	IDA		Rat	PMID:9895278\|RGD:11535093
Cellular Component	GO:0044305	calyx of Held	Unc13b	IDA		Mouse	PMID:23658173
Cellular Component	GO:0005829	cytosol	UNC13B	IDA		Human	PMID:10233166
Cellular Component	GO:0005829	cytosol	UNC13B	IDA		Human	PMID:16138900
Cellular Component	GO:0005829	cytosol	Unc13b	IDA		Rat	PMID:9895278\|RGD:11535093
Cellular Component	GO:0032009	early phagosome	Unc13b	IDA		Mouse	MGI:MGI:5467668\|PMID:23197834
Cellular Component	GO:0098978	glutamatergic synapse	Unc13b	IDA		Mouse	PMID:19700493
Cellular Component	GO:0098978	glutamatergic synapse	Unc13b	IMP		Mouse	PMID:19700493
Cellular Component	GO:0005794	Golgi apparatus	UNC13B	IDA		Human	PMID:10233166
Cellular Component	GO:0005794	Golgi apparatus	UNC13B	IDA		Human	PMID:16138900
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Unc13b	IDA		Mouse	PMID:19700493
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Unc13b	IMP		Mouse	PMID:19700493
Cellular Component	GO:0016020	membrane	UNC13B	IDA		Human	PMID:9607201
Cellular Component	GO:0031594	neuromuscular junction	Unc13b	IDA		Mouse	PMID:15988013
Cellular Component	GO:0005886	plasma membrane	Unc13b	IGI	UniProtKB:Q9JIR4	Rat	PMID:21262469\|RGD:10047275
Cellular Component	GO:0098793	presynapse	Unc13b	IDA		Mouse	PMID:23658173
Cellular Component	GO:0048786	presynaptic active zone	Unc13b	IDA		Mouse	MGI:MGI:5428060\|PMID:22674279
Cellular Component	GO:0097470	ribbon synapse	Unc13b	IDA		Mouse	MGI:MGI:5428060\|PMID:22674279
Cellular Component	GO:0097060	synaptic membrane	Unc13b	IDA		Rat	PMID:9895278\|RGD:11535093
Cellular Component	GO:0043195	terminal bouton	Unc13b	IGI	UniProtKB:Q99NE5\|UniProtKB:Q9EQZ7	Rat	PMID:21262469\|RGD:10047275
Biological Process	GO:0060478	acrosomal vesicle exocytosis	UNC13B	IDA		Human	PMID:22248876
Biological Process	GO:0071333	cellular response to glucose stimulus	UNC13B	IDA		Human	PMID:19641095
Biological Process	GO:0071333	cellular response to glucose stimulus	Unc13b	IMP		Rat	PMID:19641095\|RGD:11535114
Biological Process	GO:0007268	chemical synaptic transmission	Unc13b	IMP	MGI:MGI:2449468	Mouse	PMID:12070347
Biological Process	GO:0061789	dense core granule priming	Unc13b	IGI	UniProtKB:Q4KUS2,UniProtKB:Q9Z1N9	Rat	PMID:26575293\|RGD:12050107
Biological Process	GO:0060384	innervation	Unc13b	IGI	MGI:MGI:3051532	Mouse	PMID:15988013
Biological Process	GO:0031914	negative regulation of synaptic plasticity	Unc13b	IGI	UniProtKB:Q8K0T7	Mouse	MGI:MGI:5490921\|PMID:23658173
Biological Process	GO:0007528	neuromuscular junction development	Unc13b	IGI	MGI:MGI:3051532	Mouse	PMID:15988013
Biological Process	GO:0099011	neuronal dense core vesicle exocytosis	Unc13b	IMP		Mouse	MGI:MGI:5476894\|PMID:23229896
Biological Process	GO:0090382	phagosome maturation	Unc13b	IMP		Mouse	MGI:MGI:5467668\|PMID:23197834
Biological Process	GO:0043065	positive regulation of apoptotic process	UNC13B	IDA		Human	PMID:10233166
Biological Process	GO:1900426	positive regulation of defense response to bacterium	Unc13b	IMP		Mouse	MGI:MGI:5467668\|PMID:23197834
Biological Process	GO:0045921	positive regulation of exocytosis	Unc13b	IMP		Rat	PMID:24356451\|RGD:11535098
Biological Process	GO:0097151	positive regulation of inhibitory postsynaptic potential	Unc13b	IGI	UniProtKB:Q4KUS2\|UniProtKB:Q9Z1N9	Rat	PMID:21262469\|RGD:10047275
Biological Process	GO:0097151	positive regulation of inhibitory postsynaptic potential	Unc13b	IGI	UniProtKB:Q99NE5\|UniProtKB:Q9EQZ7	Rat	PMID:21262469\|RGD:10047275
Biological Process	GO:0050714	positive regulation of protein secretion	UNC13B	IDA		Human	PMID:19641095
Biological Process	GO:0050714	positive regulation of protein secretion	Unc13b	IMP		Rat	PMID:19641095\|RGD:11535114
Biological Process	GO:0010808	positive regulation of synaptic vesicle priming	Unc13b	IGI	UniProtKB:Q4KUS2\|UniProtKB:Q9Z1N9	Rat	PMID:21262469\|RGD:10047275
Biological Process	GO:0010808	positive regulation of synaptic vesicle priming	Unc13b	IGI	UniProtKB:Q99NE5\|UniProtKB:Q9EQZ7	Rat	PMID:21262469\|RGD:10047275
Biological Process	GO:0099525	presynaptic dense core vesicle exocytosis	Unc13b	IMP		Mouse	MGI:MGI:5819330\|PMID:26575293
Biological Process	GO:0099161	regulation of presynaptic dense core granule exocytosis	Unc13b	IDA		Rat	PMID:31679900\|RGD:155230690
Biological Process	GO:0099161	regulation of presynaptic dense core granule exocytosis	Unc13b	IMP		Rat	PMID:31679900\|RGD:155230690
Biological Process	GO:0048172	regulation of short-term neuronal synaptic plasticity	Unc13b	IMP		Mouse	MGI:MGI:5795822\|PMID:19700493
Biological Process	GO:0048172	regulation of short-term neuronal synaptic plasticity	Unc13b	IMP	MGI:MGI:2449706	Mouse	PMID:11832228
Biological Process	GO:0061669	spontaneous neurotransmitter secretion	Unc13b	IGI	UniProtKB:Q99NE5\|UniProtKB:Q9EQZ7	Rat	PMID:21262469\|RGD:10047275
Biological Process	GO:0035249	synaptic transmission, glutamatergic	Unc13b	IMP	MGI:MGI:2449706	Mouse	PMID:11832228
Biological Process	GO:0035249	synaptic transmission, glutamatergic	Unc13b	IGI	MGI:MGI:3051532	Mouse	PMID:11792326
Biological Process	GO:0016081	synaptic vesicle docking	Unc13b	IGI	MGI:MGI:3051532	Mouse	PMID:19558619
Biological Process	GO:0016079	synaptic vesicle exocytosis	Unc13b	IDA		Mouse	PMID:19700493
Biological Process	GO:0016079	synaptic vesicle exocytosis	Unc13b	IMP		Mouse	PMID:19700493
Biological Process	GO:0016082	synaptic vesicle priming	Unc13b	IMP		Mouse	MGI:MGI:2158113\|PMID:11832228
Biological Process	GO:0016082	synaptic vesicle priming	Unc13b	IGI	UniProtKB:Q4KUS2	Mouse	MGI:MGI:5617001\|PMID:25374362
Biological Process	GO:0016082	synaptic vesicle priming	Unc13b	IMP	MGI:MGI:2449706	Mouse	PMID:12070347
Biological Process	GO:0016082	synaptic vesicle priming	Unc13b	IMP		Rat	PMID:22966208\|RGD:11535109

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.