Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UNG
  • Mouse genes Ung
  • Rat genes Ung
  • Zfish genes unga,ungb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ung

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003684	damaged DNA binding	UNG	IDA		Human	PMID:18973764
Molecular Function	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity	unga	IDA		Zfish	PMID:24739389
Molecular Function	GO:0046976	histone H3K27 methyltransferase activity	unga	IDA		Zfish	PMID:24739389
Molecular Function	GO:0005515	protein binding	UNG	IPI	UniProtKB:P15927	Human	PMID:10982866
Molecular Function	GO:0005515	protein binding	UNG	IPI	UniProtKB:P23396	Human	PMID:18973764
Molecular Function	GO:0005515	protein binding	UNG	IPI	UniProtKB:P15927	Human	PMID:24910198
Molecular Function	GO:0043024	ribosomal small subunit binding	UNG	IPI	UniProtKB:P23396	Human	PMID:18973764
Molecular Function	GO:0004844	uracil DNA N-glycosylase activity	Ung	IMP	MGI:MGI:2182610	Mouse	PMID:15494304
Molecular Function	GO:0004844	uracil DNA N-glycosylase activity	Ung	IDA		Mouse	PMID:10871356
Molecular Function	GO:0004844	uracil DNA N-glycosylase activity	Ung	IDA		Rat	PMID:11292851|RGD:1599704
Molecular Function	GO:0004844	uracil DNA N-glycosylase activity	Ung	IDA		Rat	PMID:12167490|RGD:634481
Cellular Component	GO:0005739	mitochondrion	UNG	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Ung	IDA		Mouse	PMID:10871356
Cellular Component	GO:0005739	mitochondrion	Ung	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Ung	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Ung	IDA		Rat	PMID:11292851|RGD:1599704
Cellular Component	GO:0005654	nucleoplasm	UNG	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Ung	IDA		Mouse	PMID:10871356
Biological Process	GO:0006284	base-excision repair	Ung	IDA		Rat	PMID:12167490|RGD:634481
Biological Process	GO:0097510	base-excision repair, AP site formation via deaminated base removal	UNG	IDA		Human	PMID:18973764
Biological Process	GO:0045190	isotype switching	Ung	IGI	MGI:MGI:1343961	Mouse	PMID:17015724
Biological Process	GO:0043066	negative regulation of apoptotic process	Ung	IMP		Rat	PMID:15297456|RGD:1599703
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	unga	IDA		Zfish	PMID:24739389
Biological Process	GO:0044030	regulation of DNA methylation	unga	IMP	ZFIN:ZDB-MRPHLNO-140819-2	Zfish	PMID:24739389
Biological Process	GO:0016446	somatic hypermutation of immunoglobulin genes	Ung	IGI	MGI:MGI:101816	Mouse	PMID:15494304
Biological Process	GO:0016446	somatic hypermutation of immunoglobulin genes	Ung	IMP	MGI:MGI:2182610	Mouse	PMID:17015724
Biological Process	GO:0016447	somatic recombination of immunoglobulin gene segments	Ung	IMP	MGI:MGI:2182610	Mouse	PMID:15494304
Biological Process	GO:0016447	somatic recombination of immunoglobulin gene segments	Ung	IGI	MGI:MGI:101816	Mouse	PMID:15494304

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern