Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Upf1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes UPF1
- Mouse genes Upf1
- Rat genes Upf1
- Zfish genes upf1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Upf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016887	ATP hydrolysis activity	UPF1	IDA		Human	PMID:30218034
Molecular Function	GO:0003682	chromatin binding	UPF1	IDA		Human	PMID:16488880
Molecular Function	GO:0036121	double-stranded DNA helicase activity	UPF1	IDA		Human	PMID:30218034
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9BZI7	Human	PMID:11163187
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9H1J1	Human	PMID:11163187
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9HAU5	Human	PMID:11163187
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q96Q15	Human	PMID:11544179
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q8IU60	Human	PMID:12417715
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9BZI7	Human	PMID:12417715
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9H1J1	Human	PMID:12417715
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9HAU5	Human	PMID:12417715
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9NPI6	Human	PMID:12417715
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q08491	Human	PMID:12881429
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q92540	Human	PMID:14636577
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9UPR3	Human	PMID:14636577
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:O95793	Human	PMID:15680326
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9BZI7	Human	PMID:15680326
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9HAU5	Human	PMID:15680326
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q14493	Human	PMID:16086026
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9HAU5	Human	PMID:16086026
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q8IU60	Human	PMID:16364915
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9NPI6	Human	PMID:16364915
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:P54098	Human	PMID:16488880
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9HAU5	Human	PMID:16488880
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9BZI7	Human	PMID:16601204
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9HAU5	Human	PMID:17468741
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9HAU5	Human	PMID:17469741
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9UKV8	Human	PMID:17932509
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9UL18	Human	PMID:17932509
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:P15170	Human	PMID:18256688
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9HAU5	Human	PMID:18256688
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:P55265	Human	PMID:18362360
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q8IYD1	Human	PMID:18447585
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9HAU5	Human	PMID:19150429
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9NPI6	Human	PMID:19150429
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9NPJ4	Human	PMID:19150429
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:P13639	Human	PMID:19417104
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:P62753	Human	PMID:19417104
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:P62913	Human	PMID:19417104
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9BZI7	Human	PMID:19417104
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9HAU5	Human	PMID:19417104
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9BZI7	Human	PMID:19478851
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9HAU5	Human	PMID:19478851
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9HAU5	Human	PMID:19503078
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9HAU5	Human	PMID:19556969
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q16630	Human	PMID:19864460
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9BZI7	Human	PMID:19864460
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q86US8	Human	PMID:20930030
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:O14746	Human	PMID:21829167
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:O14773	Human	PMID:21829167
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q96AP0	Human	PMID:21829167
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q92540	Human	PMID:23348841
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:O95793	Human	PMID:23722113
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:P17844	Human	PMID:23788676
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9UN81	Human	PMID:24267889
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9HCE1	Human	PMID:24726324
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:P19712:PRO_0000038050	Human	PMID:24965446
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:P11940	Human	PMID:25220460
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q14147	Human	PMID:25220460
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9HAU5	Human	PMID:25220460
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q13835	Human	PMID:25225333
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9Y446	Human	PMID:25225333
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q5D1E7	Human	PMID:26000482
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q5D1E7	Human	PMID:26255671
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q14147	Human	PMID:26841701
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:Q9NUL5	Human	PMID:27974568
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:P15170	Human	PMID:9620853
Molecular Function	GO:0005515	protein binding	UPF1	IPI	UniProtKB:P62495	Human	PMID:9620853
Molecular Function	GO:0005515	protein binding	Upf1	IPI	UniProtKB:Q7TMF2	Mouse	MGI:MGI:5925577\|PMID:23202588
Molecular Function	GO:0044877	protein-containing complex binding	UPF1	IPI	UniProtKB:Q8ND04,UniProtKB:Q96Q15,UniProtKB:Q9H0W8	Human	PMID:26841701
Molecular Function	GO:0003723	RNA binding	UPF1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	UPF1	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	UPF1	IDA		Human	PMID:24726324
Molecular Function	GO:0003724	RNA helicase activity	UPF1	IDA		Human	PMID:12554878
Molecular Function	GO:0003724	RNA helicase activity	UPF1	IDA		Human	PMID:21419344
Molecular Function	GO:0042162	telomeric DNA binding	UPF1	IDA		Human	PMID:17916692
Molecular Function	GO:0042162	telomeric DNA binding	UPF1	IDA		Human	PMID:21829167
Cellular Component	GO:0000785	chromatin	UPF1	IDA		Human	PMID:16488880
Cellular Component	GO:0000781	chromosome, telomeric region	UPF1	IDA		Human	PMID:21829167
Cellular Component	GO:0005829	cytosol	UPF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0035145	exon-exon junction complex	UPF1	IDA		Human	PMID:16601204
Cellular Component	GO:0005654	nucleoplasm	UPF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	UPF1	IDA		Human	PMID:18362360
Cellular Component	GO:0044530	supraspliceosomal complex	UPF1	IDA		Human	PMID:18362360
Biological Process	GO:0061158	3'-UTR-mediated mRNA destabilization	UPF1	IDA		Human	PMID:24726324
Biological Process	GO:0061158	3'-UTR-mediated mRNA destabilization	UPF1	IMP		Human	PMID:26255671
Biological Process	GO:0044770	cell cycle phase transition	UPF1	IMP		Human	PMID:16488880
Biological Process	GO:0071347	cellular response to interleukin-1	UPF1	IDA		Human	PMID:26255671
Biological Process	GO:0071222	cellular response to lipopolysaccharide	UPF1	IDA		Human	PMID:26255671
Biological Process	GO:0043009	chordate embryonic development	upf1	IMP		Zfish	PMID:21227923\|ZFIN:ZDB-PUB-110119-26
Biological Process	GO:0043009	chordate embryonic development	upf1	IMP	ZFIN:ZDB-MRPHLNO-090714-1,ZFIN:ZDB-MRPHLNO-090714-2	Zfish	PMID:19414594
Biological Process	GO:0032508	DNA duplex unwinding	UPF1	IDA		Human	PMID:30218034
Biological Process	GO:0006281	DNA repair	UPF1	IDA		Human	PMID:16488880
Biological Process	GO:0006260	DNA replication	UPF1	IMP		Human	PMID:16488880
Biological Process	GO:0071044	histone mRNA catabolic process	UPF1	IMP		Human	PMID:16086026
Biological Process	GO:0000956	nuclear-transcribed mRNA catabolic process	UPF1	IMP		Human	PMID:23828042
Biological Process	GO:0000956	nuclear-transcribed mRNA catabolic process	upf1	IMP		Zfish	PMID:23828042\|ZFIN:ZDB-PUB-130711-11
Biological Process	GO:0000956	nuclear-transcribed mRNA catabolic process	upf1	IGI	ZFIN:ZDB-GENE-030131-5475	Zfish	PMID:28648842
Biological Process	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	UPF1	IDA		Human	PMID:17468741
Biological Process	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	UPF1	IMP		Human	PMID:18369367
Biological Process	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	upf1	IMP		Zfish	PMID:21227923\|ZFIN:ZDB-PUB-110119-26
Biological Process	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	upf1	IMP	ZFIN:ZDB-MRPHLNO-090714-2	Zfish	PMID:19414594
Biological Process	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	upf1	IMP	ZFIN:ZDB-MRPHLNO-090714-1	Zfish	PMID:19414594
Biological Process	GO:0000294	nuclear-transcribed mRNA catabolic process, RNase MRP-dependent	UPF1	IMP		Human	PMID:26255671
Biological Process	GO:0061014	positive regulation of mRNA catabolic process	UPF1	IDA		Human	PMID:24726324
Biological Process	GO:0061014	positive regulation of mRNA catabolic process	UPF1	IMP		Human	PMID:25225333
Biological Process	GO:0061014	positive regulation of mRNA catabolic process	UPF1	IMP		Human	PMID:26255671
Biological Process	GO:2000624	positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	upf1	IMP	ZFIN:ZDB-GENO-210930-1	Zfish	PMID:32571908
Biological Process	GO:0010468	regulation of gene expression	upf1	IMP	ZFIN:ZDB-MRPHLNO-090714-2	Zfish	PMID:32502192
Biological Process	GO:0032204	regulation of telomere maintenance	UPF1	IMP		Human	PMID:17916692
Biological Process	GO:0006449	regulation of translational termination	UPF1	IMP		Human	PMID:9620853
Biological Process	GO:0033077	T cell differentiation in thymus	upf1	IGI	ZFIN:ZDB-GENO-211005-1	Zfish	PMID:32571908
Biological Process	GO:0033077	T cell differentiation in thymus	upf1	IMP	ZFIN:ZDB-GENO-210930-1	Zfish	PMID:32571908
Biological Process	GO:0032201	telomere maintenance via semi-conservative replication	UPF1	IDA		Human	PMID:21829167

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.