Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UPK3A
  • Mouse genes Upk3a
  • Rat genes Upk3a
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Upk3a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	UPK3A	IPI	UniProtKB:O43765	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UPK3A	IPI	UniProtKB:Q96EQ0	Human	PMID:32296183
Cellular Component	GO:0016324	apical plasma membrane	Upk3a	IDA		Mouse	PMID:12388410
Cellular Component	GO:0016324	apical plasma membrane	Upk3a	IDA		Mouse	PMID:8175808
Cellular Component	GO:0120001	apical plasma membrane urothelial plaque	Upk3a	IDA		Mouse	PMID:22323295
Cellular Component	GO:0120001	apical plasma membrane urothelial plaque	Upk3a	EXP		Mouse	PMID:26046524
Cellular Component	GO:0070062	extracellular exosome	UPK3A	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	UPK3A	HDA		Human	PMID:23533145
Biological Process	GO:0000902	cell morphogenesis	Upk3a	IMP	MGI:MGI:2183244	Mouse	PMID:12388410
Biological Process	GO:0030855	epithelial cell differentiation	UPK3A	IDA		Human	PMID:10514386
Biological Process	GO:0001822	kidney development	Upk3a	IMP	MGI:MGI:2183244	Mouse	PMID:12388410
Biological Process	GO:0055075	potassium ion homeostasis	Upk3a	IMP	MGI:MGI:2183244	Mouse	PMID:12388410
Biological Process	GO:0055078	sodium ion homeostasis	Upk3a	IMP	MGI:MGI:2183244	Mouse	PMID:12388410
Biological Process	GO:0015840	urea transport	Upk3a	IMP	MGI:MGI:2183244	Mouse	PMID:12388410
Biological Process	GO:0060157	urinary bladder development	Upk3a	IMP	MGI:MGI:2183244	Mouse	PMID:12388410
Biological Process	GO:0006833	water transport	Upk3a	IMP	MGI:MGI:2183244	Mouse	PMID:12388410

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern