Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP15
  • Mouse genes Usp15
  • Rat genes Usp15
  • Zfish genes usp15
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp15

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP15	IDA		Human	PMID:16005295
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP15	IDA		Human	PMID:21947082
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP15	IDA		Human	PMID:22344298
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP15	IDA		Human	PMID:24526689
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP15	IDA		Human	PMID:27368102
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP15	IDA		Human	PMID:33093067
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	Usp15	IDA		Mouse	PMID:12532266
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	Usp15	IDA		Rat	PMID:10880343|RGD:634484
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	USP15	IMP		Human	PMID:21947082
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	USP15	IMP		Human	PMID:22344298
Molecular Function	GO:0101005	deubiquitinase activity	USP15	IDA		Human	PMID:32839293
Molecular Function	GO:0101005	deubiquitinase activity	Usp15	IMP		Mouse	PMID:32101751
Molecular Function	GO:0008047	enzyme activator activity	USP15	IDA		Human	PMID:32839293
Molecular Function	GO:0042802	identical protein binding	USP15	IPI	UniProtKB:Q9Y4E8	Human	PMID:22001210
Molecular Function	GO:1990380	K48-linked deubiquitinase activity	USP15	IDA		Human	PMID:24399297
Molecular Function	GO:0005515	protein binding	USP15	IPI	UniProtKB:Q9BTM9	Human	PMID:21209336
Molecular Function	GO:0005515	protein binding	USP15	IPI	UniProtKB:Q0VD86	Human	PMID:21750715
Molecular Function	GO:0005515	protein binding	USP15	IPI	UniProtKB:Q15020	Human	PMID:24526689
Molecular Function	GO:0005515	protein binding	USP15	IPI	UniProtKB:P19474	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP15	IPI	UniProtKB:Q2TAC2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP15	IPI	UniProtKB:Q96EA4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP15	IPI	UniProtKB:Q9H257	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP15	IPI	UniProtKB:Q9Y6D9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP15	IPI	UniProtKB:Q13501	Human	PMID:27368102
Molecular Function	GO:0005515	protein binding	USP15	IPI	UniProtKB:Q86TM6	Human	PMID:31477895
Molecular Function	GO:0005515	protein binding	USP15	IPI	UniProtKB:Q9H257	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	USP15	IPI	UniProtKB:Q6ZNK6	Human	PMID:32101751
Molecular Function	GO:0046332	SMAD binding	USP15	IPI	UniProtKB:P84022	Human	PMID:21947082
Molecular Function	GO:0046332	SMAD binding	USP15	IPI	UniProtKB:Q15796	Human	PMID:21947082
Molecular Function	GO:0046332	SMAD binding	USP15	IPI	UniProtKB:Q15797	Human	PMID:21947082
Molecular Function	GO:0046332	SMAD binding	USP15	IPI	UniProtKB:O15105	Human	PMID:22344298
Molecular Function	GO:0005160	transforming growth factor beta receptor binding	USP15	IPI	UniProtKB:P36897	Human	PMID:22344298
Molecular Function	GO:0061649	ubiquitin modification-dependent histone binding	USP15	IDA		Human	PMID:24526689
Cellular Component	GO:0005737	cytoplasm	USP15	IDA		Human	PMID:21947082
Cellular Component	GO:0005737	cytoplasm	USP15	IDA		Human	PMID:24526689
Cellular Component	GO:0005737	cytoplasm	Usp15	IDA		Rat	PMID:10880343|RGD:634484
Cellular Component	GO:0005829	cytosol	USP15	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Usp15	IDA		Rat	PMID:10880343|RGD:634484
Cellular Component	GO:0016604	nuclear body	USP15	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	USP15	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	USP15	IDA		Human	PMID:21947082
Cellular Component	GO:0005634	nucleus	USP15	IDA		Human	PMID:24526689
Cellular Component	GO:0005634	nucleus	Usp15	IDA		Rat	PMID:10880343|RGD:634484
Biological Process	GO:0030509	BMP signaling pathway	USP15	IDA		Human	PMID:21947082
Biological Process	GO:1904888	cranial skeletal system development	usp15	IMP	ZFIN:ZDB-MRPHLNO-100217-8	Zfish	PMID:28450118
Biological Process	GO:0009953	dorsal/ventral pattern formation	usp15	IMP	ZFIN:ZDB-MRPHLNO-100217-8	Zfish	PMID:20040115
Biological Process	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination	USP15	IDA		Human	PMID:24526689
Biological Process	GO:0035520	monoubiquitinated protein deubiquitination	USP15	IDA		Human	PMID:21947082
Biological Process	GO:0035520	monoubiquitinated protein deubiquitination	USP15	IDA		Human	PMID:24399297
Biological Process	GO:1905035	negative regulation of antifungal innate immune response	USP15	IDA		Human	PMID:33093067
Biological Process	GO:0060389	pathway-restricted SMAD protein phosphorylation	USP15	IMP		Human	PMID:22344298
Biological Process	GO:1900246	positive regulation of RIG-I signaling pathway	USP15	IDA		Human	PMID:24399297
Biological Process	GO:0016579	protein deubiquitination	USP15	IDA		Human	PMID:16005295
Biological Process	GO:0016579	protein deubiquitination	USP15	IDA		Human	PMID:22344298
Biological Process	GO:0016579	protein deubiquitination	USP15	IDA		Human	PMID:27368102
Biological Process	GO:0016579	protein deubiquitination	Usp15	IMP		Mouse	PMID:32101751
Biological Process	GO:0016579	protein deubiquitination	Usp15	IDA		Rat	PMID:10880343|RGD:634484
Biological Process	GO:1990167	protein K27-linked deubiquitination	USP15	IDA		Human	PMID:33093067
Biological Process	GO:1902238	regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	Usp15	IMP		Mouse	PMID:32101751
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	USP15	IDA		Human	PMID:21947082
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	USP15	IMP		Human	PMID:22344298

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern