Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP17L1,USP17L10,USP17L11,USP17L12,USP17L13,USP17L15,USP17L17,USP17L18,USP17L19,USP17L2,USP17L20,USP17L21,USP17L22,USP17L23,USP17L24,USP17L25,USP17L26,USP17L27,USP17L28,USP17L29,USP17L3,USP17L30,USP17L4,USP17L5,USP17L6P,USP17L7,USP17L8
  • Mouse genes Usp17lc
  • Rat genes LOC100910107,LOC689730
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp17lc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP17L24	IMP		Human	PMID:10936051
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP17L24	IMP		Human	PMID:17109758
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP17L6P	IDA		Human	PMID:17109758
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP17L2	IMP		Human	PMID:19188362
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP17L2	IDA		Human	PMID:20228808
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP17L2	IMP		Human	PMID:20228808
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP17L2	IMP		Human	PMID:20368735
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP17L2	IDA		Human	PMID:21239494
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	Usp17lc	IDA		Mouse	PMID:8995226
Molecular Function	GO:0005540	hyaluronic acid binding	USP17L24	IDA		Human	PMID:17109758
Molecular Function	GO:0005515	protein binding	USP17L2	IPI	UniProtKB:Q9H7L9	Human	PMID:21239494
Molecular Function	GO:0003723	RNA binding	USP17L24	IDA		Human	PMID:17109758
Cellular Component	GO:0005737	cytoplasm	USP17L6P	IDA		Human	PMID:17109758
Cellular Component	GO:0005789	endoplasmic reticulum membrane	USP17L2	IDA		Human	PMID:19188362
Cellular Component	GO:0005730	nucleolus	USP17L24	IDA		Human	PMID:17109758
Cellular Component	GO:0005634	nucleus	USP17L24	IDA		Human	PMID:17109758
Cellular Component	GO:0005634	nucleus	USP17L6P	IDA		Human	PMID:17109758
Cellular Component	GO:0005634	nucleus	USP17L2	IDA		Human	PMID:21239494
Biological Process	GO:0071586	CAAX-box protein processing	USP17L2	IMP		Human	PMID:19188362
Biological Process	GO:0043009	chordate embryonic development	Usp17lc	IMP		Mouse	MGI:MGI:5462517|PMID:22984479
Biological Process	GO:0034260	negative regulation of GTPase activity	USP17L2	IDA		Human	PMID:19188362
Biological Process	GO:0031064	negative regulation of histone deacetylation	USP17L2	IMP		Human	PMID:21239494
Biological Process	GO:0010955	negative regulation of protein processing	USP17L2	IMP		Human	PMID:19188362
Biological Process	GO:0090315	negative regulation of protein targeting to membrane	USP17L2	IMP		Human	PMID:19188362
Biological Process	GO:1904037	positive regulation of epithelial cell apoptotic process	USP17L24	IMP		Human	PMID:17109758
Biological Process	GO:0043547	positive regulation of GTPase activity	USP17L2	IMP		Human	PMID:21448158
Biological Process	GO:1900245	positive regulation of MDA-5 signaling pathway	USP17L2	IMP		Human	PMID:20368735
Biological Process	GO:1900246	positive regulation of RIG-I signaling pathway	USP17L2	IMP		Human	PMID:20368735
Biological Process	GO:0016579	protein deubiquitination	USP17L2	IDA		Human	PMID:20228808
Biological Process	GO:0016579	protein deubiquitination	Usp17lc	IDA		Mouse	PMID:8995226
Biological Process	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	USP17L24	IMP		Human	PMID:10936051
Biological Process	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	USP17L24	IMP		Human	PMID:17109758
Biological Process	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	USP17L6P	IDA		Human	PMID:17109758
Biological Process	GO:0071108	protein K48-linked deubiquitination	USP17L2	IMP		Human	PMID:19188362
Biological Process	GO:0071108	protein K48-linked deubiquitination	USP17L2	IMP		Human	PMID:20368735
Biological Process	GO:0070536	protein K63-linked deubiquitination	USP17L2	IMP		Human	PMID:19188362
Biological Process	GO:0070536	protein K63-linked deubiquitination	USP17L2	IMP		Human	PMID:20368735
Biological Process	GO:0070536	protein K63-linked deubiquitination	USP17L2	IDA		Human	PMID:21239494
Biological Process	GO:0042981	regulation of apoptotic process	USP17L2	IMP		Human	PMID:21239494
Biological Process	GO:0030334	regulation of cell migration	USP17L2	IMP		Human	PMID:21448158
Biological Process	GO:0042127	regulation of cell population proliferation	USP17L2	IMP		Human	PMID:19188362
Biological Process	GO:0050691	regulation of defense response to virus by host	USP17L2	IMP		Human	PMID:20368735
Biological Process	GO:0110030	regulation of G2/MI transition of meiotic cell cycle	USP17L2	IMP		Human	PMID:20228808
Biological Process	GO:1900027	regulation of ruffle assembly	USP17L2	IMP		Human	PMID:21448158

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern