Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP21
  • Mouse genes Usp21
  • Rat genes Usp21
  • Zfish genes usp21
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp21

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP21	IDA		Human	PMID:10799498
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP21	IMP		Human	PMID:26100909
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	Usp21	IDA		Mouse	MGI:MGI:3846030|PMID:18172164
Molecular Function	GO:0008234	cysteine-type peptidase activity	USP21	IMP		Human	PMID:10799498
Molecular Function	GO:0008234	cysteine-type peptidase activity	Usp21	IDA		Mouse	MGI:MGI:3846030|PMID:18172164
Molecular Function	GO:0019784	deNEDDylase activity	USP21	IDA		Human	PMID:10799498
Molecular Function	GO:0005515	protein binding	USP21	IPI	UniProtKB:P09936	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	USP21	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP21	IPI	UniProtKB:Q5T5X7	Human	PMID:26100909
Molecular Function	GO:0005515	protein binding	USP21	IPI	UniProtKB:Q9UIF9	Human	PMID:26100909
Molecular Function	GO:0005515	protein binding	USP21	IPI	UniProtKB:O95967	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP21	IPI	UniProtKB:Q16630-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP21	IPI	UniProtKB:Q6UY14-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP21	IPI	UniProtKB:Q7L273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP21	IPI	UniProtKB:Q9NYD6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP21	IPI	UniProtKB:P09936	Human	PMID:32814053
Molecular Function	GO:0003713	transcription coactivator activity	Usp21	IDA		Mouse	MGI:MGI:3846030|PMID:18172164
Cellular Component	GO:0005829	cytosol	USP21	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	USP21	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	USP21	IDA		Human	GO_REF:0000052
Biological Process	GO:0021551	central nervous system morphogenesis	usp21	IMP	ZFIN:ZDB-MRPHLNO-100217-14	Zfish	PMID:20040115
Biological Process	GO:1904888	cranial skeletal system development	usp21	IMP	ZFIN:ZDB-MRPHLNO-100217-14	Zfish	PMID:28450118
Biological Process	GO:0031175	neuron projection development	Usp21	IMP		Rat	PMID:22298430|RGD:9587462
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	Usp21	IDA		Mouse	MGI:MGI:3846030|PMID:18172164

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern