Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP22
  • Mouse genes Usp22
  • Rat genes Usp22
  • Zfish genes usp22
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp22

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP22	IMP		Human	PMID:18206973
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP22	IDA		Human	PMID:16378762
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	Usp22	IDA		Mouse	PMID:16378762
Molecular Function	GO:0019899	enzyme binding	USP22	IPI	UniProtKB:Q96EB6	Human	PMID:23382074
Molecular Function	GO:0140936	histone H2B deubiquitinase activity	USP22	IDA		Human	PMID:18469533
Molecular Function	GO:0010485	histone H4 acetyltransferase activity	USP22	IDA		Human	PMID:18206973
Molecular Function	GO:0030374	nuclear receptor coactivator activity	USP22	IMP		Human	PMID:18206972
Molecular Function	GO:0005515	protein binding	USP22	IPI	UniProtKB:Q14CW9	Human	PMID:18206972
Molecular Function	GO:0005515	protein binding	USP22	IPI	UniProtKB:Q9NRN7	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	USP22	IPI	UniProtKB:Q96AE4	Human	PMID:21779003
Molecular Function	GO:0005515	protein binding	USP22	IPI	UniProtKB:Q13469	Human	PMID:24561192
Molecular Function	GO:0005515	protein binding	USP22	IPI	UniProtKB:Q9NRN7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP22	IPI	UniProtKB:Q14CW9	Human	PMID:27601583
Molecular Function	GO:0005515	protein binding	USP22	IPI	UniProtKB:Q96GX2	Human	PMID:27601583
Molecular Function	GO:0005515	protein binding	USP22	IPI	UniProtKB:Q96JN0	Human	PMID:29628311
Molecular Function	GO:0003713	transcription coactivator activity	USP22	IDA		Human	PMID:18206972
Cellular Component	GO:0000124	SAGA complex	USP22	IDA		Human	PMID:18206972
Cellular Component	GO:0000124	SAGA complex	USP22	IDA		Human	PMID:18206973
Cellular Component	GO:0000124	SAGA complex	USP22	IDA		Human	PMID:27601583
Biological Process	GO:0016578	histone deubiquitination	USP22	IDA		Human	PMID:18206972
Biological Process	GO:0043966	histone H3 acetylation	USP22	IDA		Human	PMID:10373431
Biological Process	GO:0035521	monoubiquitinated histone deubiquitination	USP22	IDA		Human	PMID:18206972
Biological Process	GO:0035522	monoubiquitinated histone H2A deubiquitination	USP22	IDA		Human	PMID:18206972
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	USP22	IMP		Human	PMID:18206973
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	USP22	IMP		Human	PMID:18206973
Biological Process	GO:0016579	protein deubiquitination	USP22	IDA		Human	PMID:16378762
Biological Process	GO:0016579	protein deubiquitination	Usp22	IDA		Mouse	PMID:16378762
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	USP22	IDA		Human	PMID:9603525

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern